Gene: ENSG00000171720 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000171720
Transcript Identifier
ENST00000305264
Gene Type
Coding gene
Location
5 : 141621468-141636790 : negative

Family Information

Homologous gene family
HOM03P000083
(314 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000073
(95 genes in 39 species)
specific family

Descriptions

gene_descr
histone deacetylase 3

Identifiers

Type Value
pidENSP00000302967
HGNC4854
UniprotO15379

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA, IMP
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001934
IDA
Genome Projectpositive regulation of protein phosphorylation
GO:0006325
TAS
Genome Projectchromatin organization
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006476
IDA
Genome Projectprotein deacetylation
GO:0007219
TAS
Genome ProjectNotch signaling pathway
GO:0007346
IEA
Genome Projectregulation of mitotic cell cycle
GO:0007623
TAS
Genome Projectcircadian rhythm
GO:0016568
TAS, IEA
Genome Projectchromatin modification
GO:0016575
IEA
Genome Projecthistone deacetylation
GO:0031647
IDA
Genome Projectregulation of protein stability
GO:0032008
IMP
Genome Projectpositive regulation of TOR signaling
GO:0032922
IEA
Genome Projectcircadian regulation of gene expression
GO:0040014
IEA
Genome Projectregulation of multicellular organism growth
GO:0042993
IDA
Genome Projectpositive regulation of transcription factor import into nucleus
GO:0043066
TAS
Genome Projectnegative regulation of apoptotic process
GO:0043433
IEA
Genome Projectnegative regulation of sequence-specific DNA binding transcription factor activity
GO:0044255
TAS
Genome Projectcellular lipid metabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0045786
TAS
Genome Projectnegative regulation of cell cycle
GO:0045892
IMP
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045944
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046329
IMP
Genome Projectnegative regulation of JNK cascade
GO:0048011
TAS
Genome Projectneurotrophin TRK receptor signaling pathway
GO:0051225
IMP
Genome Projectspindle assembly
GO:0070932
IEA
Genome Projecthistone H3 deacetylation
GO:0071498
IDA
Genome Projectcellular response to fluid shear stress
GO:1903507
ISS
Genome Projectnegative regulation of nucleic acid-templated transcription
GO:2000726
IEA
Genome Projectnegative regulation of cardiac muscle cell differentiation
GO:0010832
IMP
Genome Projectnegative regulation of myotube differentiation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003682
IDA
Genome Projectchromatin binding
GO:0003714
IDA, IMP
ISS
Genome Projecttranscription corepressor activity
GO:0004407
IMP
TAS, IEA
Genome Projecthistone deacetylase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
IPI
TAS
Genome Projecttranscription factor binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0019899
IPI
Genome Projectenzyme binding
GO:0030332
IPI
Genome Projectcyclin binding
GO:0031490
IEA
Genome Projectchromatin DNA binding
GO:0032041
IEA
Genome ProjectNAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0033558
IDA
Genome Projectprotein deacetylase activity
GO:0042826
IPI
Genome Projecthistone deacetylase binding
GO:0051059
IPI
Genome ProjectNF-kappaB binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000118
TAS
Genome Projecthistone deacetylase complex
GO:0005634
IDA
TAS, IEA
Genome Projectnucleus
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005737
IDA
TAS, IEA
Genome Projectcytoplasm
GO:0005794
IDA
Genome ProjectGolgi apparatus
GO:0005829
IDA
IEA
Genome Projectcytosol
GO:0005876
IDA
Genome Projectspindle microtubule
GO:0005886
IDA
Genome Projectplasma membrane
GO:0017053
IDA
Genome Projecttranscriptional repressor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000286Histone deacetylase superfamily
IPR003084Histone deacetylase
IPR023801Histone deacetylase domain

No MapMan annotations defined for this gene.