Gene: ENSG00000171552 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000171552
Transcript Identifier
ENST00000307677
Gene Type
Coding gene
Location
20 : 31665949-31722218 : negative

Family Information

Homologous gene family
HOM03P011025
(7 genes in 3 species)
specific family

Descriptions

gene_descr
BCL2-like 1

Identifiers

Type Value
pidENSP00000302564
HGNC992
UniprotQ07817

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000910
IMP
Genome Projectcytokinesis
GO:0001541
IEA
Genome Projectovarian follicle development
GO:0001701
IEA
Genome Projectin utero embryonic development
GO:0001836
IDA
Genome Projectrelease of cytochrome c from mitochondria
GO:0006897
IEA
Genome Projectendocytosis
GO:0006915
TAS, IEA
Genome Projectapoptotic process
GO:0007093
IMP
Genome Projectmitotic cell cycle checkpoint
GO:0007281
IEA
Genome Projectgerm cell development
GO:0007283
IEA
Genome Projectspermatogenesis
GO:0008283
IEA
Genome Projectcell proliferation
GO:0008284
IEA
Genome Projectpositive regulation of cell proliferation
GO:0008584
IEA
Genome Projectmale gonad development
GO:0008630
IBA
IEA
Genome Projectintrinsic apoptotic signaling pathway in response to DNA damage
GO:0008637
TAS
Genome Projectapoptotic mitochondrial changes
GO:0009314
IEA
Genome Projectresponse to radiation
GO:0009566
IEA
Genome Projectfertilization
GO:0009615
IEA
Genome Projectresponse to virus
GO:0010507
TAS
Genome Projectnegative regulation of autophagy
GO:0012501
TAS
Genome Projectprogrammed cell death
GO:0019050
IDA
Genome Projectsuppression by virus of host apoptotic process
GO:0034097
IDA
Genome Projectresponse to cytokine
GO:0035872
TAS
Genome Projectnucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0040007
IEA
Genome Projectgrowth
GO:0042981
IEA
Genome Projectregulation of apoptotic process
GO:0043065
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043066
IDA, IMP
Genome Projectnegative regulation of apoptotic process
GO:0043524
IEA
Genome Projectnegative regulation of neuron apoptotic process
GO:0045087
TAS
Genome Projectinnate immune response
GO:0046898
IEA
Genome Projectresponse to cycloheximide
GO:0046902
IDA
Genome Projectregulation of mitochondrial membrane permeability
GO:0051402
IEA
Genome Projectneuron apoptotic process
GO:0051881
IDA
Genome Projectregulation of mitochondrial membrane potential
GO:0060154
IEA
Genome Projectcellular process regulating host cell cycle in response to virus
GO:0070584
IEA
Genome Projectmitochondrion morphogenesis
GO:0071230
IEA
Genome Projectcellular response to amino acid stimulus
GO:0071312
IEA
Genome Projectcellular response to alkaloid
GO:0071480
IEA
Genome Projectcellular response to gamma radiation
GO:0071839
IEA
Genome Projectapoptotic process in bone marrow
GO:0090005
IDA
Genome Projectnegative regulation of establishment of protein localization to plasma membrane
GO:0090201
IDA
IC
Genome Projectnegative regulation of release of cytochrome c from mitochondria
GO:0097192
IBA
IEA
Genome Projectextrinsic apoptotic signaling pathway in absence of ligand
GO:0097193
TAS
Genome Projectintrinsic apoptotic signaling pathway
GO:0097284
IEA
Genome Projecthepatocyte apoptotic process
GO:1900118
IDA
Genome Projectnegative regulation of execution phase of apoptosis
GO:1902230
IDA
Genome Projectnegative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:2000811
IMP
Genome Projectnegative regulation of anoikis
GO:2001240
TAS
Genome Projectnegative regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO:2001243
IDA
Genome Projectnegative regulation of intrinsic apoptotic signaling pathway
GO:2001244
TAS
Genome Projectpositive regulation of intrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0019901
IPI
Genome Projectprotein kinase binding
GO:0042802
IPI
Genome Projectidentical protein binding
GO:0042803
IBA
Genome Projectprotein homodimerization activity
GO:0046982
IBA
IEA
Genome Projectprotein heterodimerization activity
GO:0051434
IPI
Genome ProjectBH3 domain binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005622
IEA
Genome Projectintracellular
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005730
IDA
Genome Projectnucleolus
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005739
IDA
TAS, IEA
Genome Projectmitochondrion
GO:0005741
IDA
TAS, NAS, IEA
Genome Projectmitochondrial outer membrane
GO:0005743
IEA
Genome Projectmitochondrial inner membrane
GO:0005759
IEA
Genome Projectmitochondrial matrix
GO:0005813
IDA
Genome Projectcentrosome
GO:0005815
IEA
Genome Projectmicrotubule organizing center
GO:0005829
IEA
Genome Projectcytosol
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030054
IEA
Genome Projectcell junction
GO:0030672
IEA
Genome Projectsynaptic vesicle membrane
GO:0031410
IEA
Genome Projectcytoplasmic vesicle
GO:0031965
IEA
Genome Projectnuclear membrane
GO:0031966
IEA
Genome Projectmitochondrial membrane
GO:0045202
IEA
Genome Projectsynapse
GO:0097136
IDA
Genome ProjectBcl-2 family protein complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002475Bcl2-like
IPR003093Apoptosis regulator, Bcl-2 protein, BH4
IPR004725Apoptosis regulator, Bcl-2/ BclX
IPR013279Apoptosis regulator, Bcl-X
IPR020717Apoptosis regulator, Bcl-2, BH1 motif, conserved site
IPR020726Apoptosis regulator, Bcl-2, BH2 motif, conserved site
IPR020728Apoptosis regulator, Bcl-2, BH3 motif, conserved site
IPR020731Apoptosis regulator, Bcl-2, BH4 motif, conserved site
IPR026298Blc2 family

No MapMan annotations defined for this gene.