Gene: ENSG00000170890 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000170890
Transcript Identifier
ENST00000308366
Gene Type
Coding gene
Location
12 : 120322193-120327753 : negative

Family Information

Homologous gene family
HOM03P012317
(7 genes in 4 species)
specific family

Descriptions

gene_descr
phospholipase A2, group IB (pancreas)

Identifiers

Type Value
pidENSP00000312286
HGNC9030
UniprotP04054

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000187
ISS
Genome Projectactivation of MAPK activity
GO:0002227
IDA
Genome Projectinnate immune response in mucosa
GO:0002446
ISS
Genome Projectneutrophil mediated immunity
GO:0006629
IEA
Genome Projectlipid metabolic process
GO:0006633
IDA
IEA
Genome Projectfatty acid biosynthetic process
GO:0006644
TAS, IEA
Genome Projectphospholipid metabolic process
GO:0006654
TAS
Genome Projectphosphatidic acid biosynthetic process
GO:0007015
TAS
Genome Projectactin filament organization
GO:0007165
TAS
Genome Projectsignal transduction
GO:0010524
ISS
Genome Projectpositive regulation of calcium ion transport into cytosol
GO:0015758
ISS
Genome Projectglucose transport
GO:0016042
IEA
Genome Projectlipid catabolic process
GO:0019370
ISS
Genome Projectleukotriene biosynthetic process
GO:0019731
IDA
Genome Projectantibacterial humoral response
GO:0030593
ISS
Genome Projectneutrophil chemotaxis
GO:0032431
TAS
Genome Projectactivation of phospholipase A2 activity
GO:0032637
ISS
Genome Projectinterleukin-8 production
GO:0032869
ISS
Genome Projectcellular response to insulin stimulus
GO:0035556
ISS
Genome Projectintracellular signal transduction
GO:0036148
TAS
Genome Projectphosphatidylglycerol acyl-chain remodeling
GO:0036149
TAS
Genome Projectphosphatidylinositol acyl-chain remodeling
GO:0036150
TAS
Genome Projectphosphatidylserine acyl-chain remodeling
GO:0036151
TAS
Genome Projectphosphatidylcholine acyl-chain remodeling
GO:0036152
TAS
Genome Projectphosphatidylethanolamine acyl-chain remodeling
GO:0044240
IDA
Genome Projectmulticellular organismal lipid catabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0045740
IDA
IEA
Genome Projectpositive regulation of DNA replication
GO:0045944
ISS
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046470
IDA
Genome Projectphosphatidylcholine metabolic process
GO:0046474
TAS
Genome Projectglycerophospholipid biosynthetic process
GO:0048146
IC
Genome Projectpositive regulation of fibroblast proliferation
GO:0050482
TAS
Genome Projectarachidonic acid secretion
GO:0050714
TAS
Genome Projectpositive regulation of protein secretion
GO:0050778
ISS
Genome Projectpositive regulation of immune response
GO:0050830
IDA
Genome Projectdefense response to Gram-positive bacterium
GO:0051092
ISS
Genome Projectpositive regulation of NF-kappaB transcription factor activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004623
IDA
IEA
Genome Projectphospholipase A2 activity
GO:0005102
IDA, IPI
IEA
Genome Projectreceptor binding
GO:0005509
IDA
IEA
Genome Projectcalcium ion binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0032052
ISS
Genome Projectbile acid binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0047498
IDA
IEA
Genome Projectcalcium-dependent phospholipase A2 activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS, IEA
Genome Projectextracellular region
GO:0005615
IDA
Genome Projectextracellular space
GO:0009986
IDA
IEA
Genome Projectcell surface
GO:0030141
IEA
Genome Projectsecretory granule

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001211Phospholipase A2
IPR013090Phospholipase A2, active site
IPR016090Phospholipase A2 domain

No MapMan annotations defined for this gene.