Gene: ENSG00000170873 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000170873
Transcript Identifier
ENST00000325064
Gene Type
Coding gene
Location
8 : 124552992-124727955 : negative

Family Information

Homologous gene family
HOM03P014645
(6 genes in 4 species)
specific family

Descriptions

gene_descr
metastasis suppressor 1

Identifiers

Type Value
pidENSP00000322804
HGNC20443
UniprotO43312

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001701
IEA
Genome Projectin utero embryonic development
GO:0002230
IMP
Genome Projectpositive regulation of defense response to virus by host
GO:0006928
NAS
Genome Projectmovement of cell or subcellular component
GO:0007009
IEA
Genome Projectplasma membrane organization
GO:0007015
IEA
Genome Projectactin filament organization
GO:0007155
NAS
Genome Projectcell adhesion
GO:0007169
TAS
Genome Projecttransmembrane receptor protein tyrosine kinase signaling pathway
GO:0010960
IEA
Genome Projectmagnesium ion homeostasis
GO:0030035
NAS
Genome Projectmicrospike assembly
GO:0030036
TAS, IEA
Genome Projectactin cytoskeleton organization
GO:0030041
IEA
Genome Projectactin filament polymerization
GO:0030282
IEA
Genome Projectbone mineralization
GO:0032233
IEA
Genome Projectpositive regulation of actin filament bundle assembly
GO:0034334
IEA
Genome Projectadherens junction maintenance
GO:0050680
ISS
Genome Projectnegative regulation of epithelial cell proliferation
GO:0061333
ISS
Genome Projectrenal tubule morphogenesis
GO:0071498
ISS
Genome Projectcellular response to fluid shear stress
GO:0072001
IEA
Genome Projectrenal system development
GO:0072102
ISS
Genome Projectglomerulus morphogenesis
GO:0072160
ISS
Genome Projectnephron tubule epithelial cell differentiation
GO:2001013
ISS
Genome Projectepithelial cell proliferation involved in renal tubule morphogenesis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003779
IEA
Genome Projectactin binding
GO:0003785
IDA
Genome Projectactin monomer binding
GO:0005102
IPI
Genome Projectreceptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0042802
IPI
Genome Projectidentical protein binding
GO:0051015
IEA
Genome Projectactin filament binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001726
NAS
Genome Projectruffle
GO:0005737
TAS, IEA
Genome Projectcytoplasm
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005912
IEA
Genome Projectadherens junction
GO:0015629
IDA
Genome Projectactin cytoskeleton
GO:0030139
TAS
Genome Projectendocytic vesicle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003124WH2 domain
IPR013606IMD/I-BAR domain
IPR027682I-BAR domain containing protein MIM
IPR030127I-BAR domain containing protein MIM/ABBA

No MapMan annotations defined for this gene.