Gene: ENSG00000170458 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000170458
Transcript Identifier
ENST00000401743
Gene Type
Coding gene
Location
5 : 140631856-140633071 : negative

Family Information

Homologous gene family
HOM03P040506
(2 genes in 2 species)
specific family

Descriptions

gene_descr
CD14 molecule

Identifiers

Type Value
pidENSP00000385519
HGNC1628
UniprotP08571

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002224
TAS
Genome Projecttoll-like receptor signaling pathway
GO:0002237
IEA
Genome Projectresponse to molecule of bacterial origin
GO:0002376
IEA
Genome Projectimmune system process
GO:0002755
TAS
Genome ProjectMyD88-dependent toll-like receptor signaling pathway
GO:0002756
TAS
Genome ProjectMyD88-independent toll-like receptor signaling pathway
GO:0006898
IEA
Genome Projectreceptor-mediated endocytosis
GO:0006909
TAS
Genome Projectphagocytosis
GO:0006915
TAS
Genome Projectapoptotic process
GO:0006954
IEA
Genome Projectinflammatory response
GO:0007166
TAS
Genome Projectcell surface receptor signaling pathway
GO:0007249
TAS
Genome ProjectI-kappaB kinase/NF-kappaB signaling
GO:0009408
IEA
Genome Projectresponse to heat
GO:0012501
TAS
Genome Projectprogrammed cell death
GO:0032026
IEA
Genome Projectresponse to magnesium ion
GO:0032481
IEA
Genome Projectpositive regulation of type I interferon production
GO:0032496
IEA
Genome Projectresponse to lipopolysaccharide
GO:0032729
ISS
Genome Projectpositive regulation of interferon-gamma production
GO:0032760
IDA, IMP
Genome Projectpositive regulation of tumor necrosis factor production
GO:0034134
TAS
Genome Projecttoll-like receptor 2 signaling pathway
GO:0034138
TAS
Genome Projecttoll-like receptor 3 signaling pathway
GO:0034142
ISS
TAS
Genome Projecttoll-like receptor 4 signaling pathway
GO:0034612
IEA
Genome Projectresponse to tumor necrosis factor
GO:0035666
TAS
Genome ProjectTRIF-dependent toll-like receptor signaling pathway
GO:0038123
TAS
Genome Projecttoll-like receptor TLR1:TLR2 signaling pathway
GO:0038124
TAS
Genome Projecttoll-like receptor TLR6:TLR2 signaling pathway
GO:0045087
TAS, IEA
Genome Projectinnate immune response
GO:0045471
IEA
Genome Projectresponse to ethanol
GO:0045807
IEA
Genome Projectpositive regulation of endocytosis
GO:0050715
IEA
Genome Projectpositive regulation of cytokine secretion
GO:0051602
IEA
Genome Projectresponse to electrical stimulus
GO:0071222
IDA, IMP
IEA
Genome Projectcellular response to lipopolysaccharide
GO:0071223
IDA
Genome Projectcellular response to lipoteichoic acid
GO:0097191
TAS
Genome Projectextrinsic apoptotic signaling pathway
GO:0097296
TAS
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001530
IDA
Genome Projectlipopolysaccharide binding
GO:0001847
TAS
Genome Projectopsonin receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0016019
TAS
Genome Projectpeptidoglycan receptor activity
GO:0070891
IDA
Genome Projectlipoteichoic acid binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS
Genome Projectextracellular region
GO:0005615
IDA
IEA
Genome Projectextracellular space
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0009986
IEA
Genome Projectcell surface
GO:0010008
TAS
Genome Projectendosome membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0031225
IEA
Genome Projectanchored component of membrane
GO:0031362
IDA
Genome Projectanchored component of external side of plasma membrane
GO:0045121
IEA
Genome Projectmembrane raft
GO:0046696
IDA
Genome Projectlipopolysaccharide receptor complex
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001611Leucine-rich repeat
IPR016337Monocyte differentiation antigen CD14

No MapMan annotations defined for this gene.