Gene: ENSG00000170430 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000170430
Transcript Identifier
ENST00000306010
Gene Type
Coding gene
Location
10 : 129467216-129766997 : positive

Family Information

Homologous gene family
HOM03P011983
(7 genes in 7 species)
specific family

Descriptions

gene_descr
O-6-methylguanine-DNA methyltransferase

Identifiers

Type Value
pidENSP00000302111
HGNC7059
UniprotP16455
UniprotB4DEE8

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006281
TAS, IEA
Genome ProjectDNA repair
GO:0006307
IBA
TAS, IEA
Genome ProjectDNA dealkylation involved in DNA repair
GO:0006974
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0009636
IEA
Genome Projectresponse to toxic substance
GO:0014070
IEA
Genome Projectresponse to organic cyclic compound
GO:0032259
IEA
Genome Projectmethylation
GO:0034599
IEA
Genome Projectcellular response to oxidative stress
GO:0042493
IEA
Genome Projectresponse to drug
GO:0043281
IEA
Genome Projectregulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045471
IEA
Genome Projectresponse to ethanol
GO:0045739
IEA
Genome Projectpositive regulation of DNA repair
GO:0051593
IEA
Genome Projectresponse to folic acid
GO:0060548
IEA
Genome Projectnegative regulation of cell death
GO:0060644
IEA
Genome Projectmammary gland epithelial cell differentiation
GO:0071407
IEA
Genome Projectcellular response to organic cyclic compound
GO:0071479
IEA
Genome Projectcellular response to ionizing radiation
GO:0006266
TAS
Genome ProjectDNA ligation
GO:0006306
TAS
Genome ProjectDNA methylation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003824
IEA
Genome Projectcatalytic activity
GO:0003908
IBA
IEA
Genome Projectmethylated-DNA-[protein]-cysteine S-methyltransferase activity
GO:0005509
IEA
Genome Projectcalcium ion binding
GO:0008168
TAS, IEA
Genome Projectmethyltransferase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0003677
TAS, IEA
Genome ProjectDNA binding
GO:0003684
IBA
Genome Projectdamaged DNA binding
GO:0009008
TAS
Genome ProjectDNA-methyltransferase activity
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
TAS, IEA
Genome Projectnucleus
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0016020
IDA
Genome Projectmembrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001497Methylated-DNA-[protein]-cysteine S-methyltransferase, active site
IPR008332Methylguanine DNA methyltransferase, ribonuclease-like domain
IPR011991Winged helix-turn-helix DNA-binding domain
IPR014048Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding

No MapMan annotations defined for this gene.