Gene: ENSG00000170315 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000170315
Transcript Identifier
ENST00000614404
Gene Type
Coding gene
Location
17 : 16381908-16382597 : positive

Family Information

Homologous gene family
HOM03P000066
(383 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P009306
(9 genes in 8 species)
specific family

Descriptions

gene_descr
ubiquitin B

Identifiers

Type Value
pidENSP00000478771
HGNC12463
UniprotP0CG47
UniprotQ5U5U6

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000082
TAS
Genome ProjectG1/S transition of mitotic cell cycle
GO:0000086
TAS
Genome ProjectG2/M transition of mitotic cell cycle
GO:0000122
TAS
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0000187
TAS
Genome Projectactivation of MAPK activity
GO:0000209
TAS
Genome Projectprotein polyubiquitination
GO:0000278
TAS
Genome Projectmitotic cell cycle
GO:0002223
TAS
Genome Projectstimulatory C-type lectin receptor signaling pathway
GO:0002224
TAS
Genome Projecttoll-like receptor signaling pathway
GO:0002474
TAS
Genome Projectantigen processing and presentation of peptide antigen via MHC class I
GO:0002479
TAS
Genome Projectantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002755
TAS
Genome ProjectMyD88-dependent toll-like receptor signaling pathway
GO:0002756
TAS
Genome ProjectMyD88-independent toll-like receptor signaling pathway
GO:0005975
TAS
Genome Projectcarbohydrate metabolic process
GO:0005978
TAS
Genome Projectglycogen biosynthetic process
GO:0006006
TAS
Genome Projectglucose metabolic process
GO:0006281
TAS
Genome ProjectDNA repair
GO:0006351
TAS
Genome Projecttranscription, DNA-templated
GO:0006367
TAS
Genome Projecttranscription initiation from RNA polymerase II promoter
GO:0006915
TAS
Genome Projectapoptotic process
GO:0006977
TAS
Genome ProjectDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007173
TAS
Genome Projectepidermal growth factor receptor signaling pathway
GO:0007179
TAS
Genome Projecttransforming growth factor beta receptor signaling pathway
GO:0007219
TAS
Genome ProjectNotch signaling pathway
GO:0007220
TAS
Genome ProjectNotch receptor processing
GO:0007249
TAS
Genome ProjectI-kappaB kinase/NF-kappaB signaling
GO:0007254
TAS
Genome ProjectJNK cascade
GO:0007623
TAS
Genome Projectcircadian rhythm
GO:0008543
TAS
Genome Projectfibroblast growth factor receptor signaling pathway
GO:0010467
TAS
Genome Projectgene expression
GO:0010939
TAS
Genome Projectregulation of necrotic cell death
GO:0012501
TAS
Genome Projectprogrammed cell death
GO:0016032
TAS
Genome Projectviral process
GO:0016197
TAS
Genome Projectendosomal transport
GO:0019058
TAS
Genome Projectviral life cycle
GO:0019068
TAS
Genome Projectvirion assembly
GO:0019082
TAS
Genome Projectviral protein processing
GO:0019221
TAS
Genome Projectcytokine-mediated signaling pathway
GO:0019985
TAS
Genome Projecttranslesion synthesis
GO:0030512
TAS
Genome Projectnegative regulation of transforming growth factor beta receptor signaling pathway
GO:0031145
TAS
Genome Projectanaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031396
IDA
Genome Projectregulation of protein ubiquitination
GO:0032479
TAS
Genome Projectregulation of type I interferon production
GO:0032480
TAS
Genome Projectnegative regulation of type I interferon production
GO:0032481
TAS
Genome Projectpositive regulation of type I interferon production
GO:0034134
TAS
Genome Projecttoll-like receptor 2 signaling pathway
GO:0034138
TAS
Genome Projecttoll-like receptor 3 signaling pathway
GO:0034142
TAS
Genome Projecttoll-like receptor 4 signaling pathway
GO:0034146
TAS
Genome Projecttoll-like receptor 5 signaling pathway
GO:0034162
TAS
Genome Projecttoll-like receptor 9 signaling pathway
GO:0034166
TAS
Genome Projecttoll-like receptor 10 signaling pathway
GO:0034220
TAS
Genome Projection transmembrane transport
GO:0035666
TAS
Genome ProjectTRIF-dependent toll-like receptor signaling pathway
GO:0035872
TAS
Genome Projectnucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0038095
TAS
Genome ProjectFc-epsilon receptor signaling pathway
GO:0038123
TAS
Genome Projecttoll-like receptor TLR1:TLR2 signaling pathway
GO:0038124
TAS
Genome Projecttoll-like receptor TLR6:TLR2 signaling pathway
GO:0042059
TAS
Genome Projectnegative regulation of epidermal growth factor receptor signaling pathway
GO:0042276
TAS
Genome Projecterror-prone translesion synthesis
GO:0042590
TAS
Genome Projectantigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042769
TAS
Genome ProjectDNA damage response, detection of DNA damage
GO:0042981
TAS
Genome Projectregulation of apoptotic process
GO:0043065
TAS
Genome Projectpositive regulation of apoptotic process
GO:0043066
TAS
Genome Projectnegative regulation of apoptotic process
GO:0043123
TAS
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0045087
TAS
Genome Projectinnate immune response
GO:0045944
TAS
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0047497
IDA
Genome Projectmitochondrion transport along microtubule
GO:0048011
TAS
Genome Projectneurotrophin TRK receptor signaling pathway
GO:0048812
IMP
Genome Projectneuron projection morphogenesis
GO:0050852
TAS
Genome ProjectT cell receptor signaling pathway
GO:0051092
TAS
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0051403
TAS
Genome Projectstress-activated MAPK cascade
GO:0051436
TAS
Genome Projectnegative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437
TAS
Genome Projectpositive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
GO:0051439
TAS
Genome Projectregulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051881
IDA
Genome Projectregulation of mitochondrial membrane potential
GO:0055085
TAS
Genome Projecttransmembrane transport
GO:0061024
TAS
Genome Projectmembrane organization
GO:0061136
IDA
Genome Projectregulation of proteasomal protein catabolic process
GO:0061418
TAS
Genome Projectregulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0070266
TAS
Genome Projectnecroptotic process
GO:0070423
TAS
Genome Projectnucleotide-binding oligomerization domain containing signaling pathway
GO:0070987
TAS
Genome Projecterror-free translesion synthesis
GO:0071456
TAS
Genome Projectcellular response to hypoxia
GO:0075733
TAS
Genome Projectintracellular transport of virus
GO:0090090
TAS
Genome Projectnegative regulation of canonical Wnt signaling pathway
GO:0090263
TAS
Genome Projectpositive regulation of canonical Wnt signaling pathway
GO:0097190
TAS
Genome Projectapoptotic signaling pathway
GO:0097300
TAS
Genome Projectprogrammed necrotic cell death
GO:1901214
IDA
Genome Projectregulation of neuron death
GO:1902255
IDA
Genome Projectpositive regulation of intrinsic apoptotic signaling pathway by p53 class mediator

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005615
IDA
Genome Projectextracellular space
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005739
IDA
Genome Projectmitochondrion
GO:0005829
TAS
Genome Projectcytosol
GO:0005886
TAS
Genome Projectplasma membrane
GO:0010008
TAS
Genome Projectendosome membrane
GO:0030666
TAS
Genome Projectendocytic vesicle membrane
GO:0043005
IDA
Genome Projectneuron projection
GO:0043025
IDA
Genome Projectneuronal cell body
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000626Ubiquitin domain
IPR019954Ubiquitin conserved site
IPR019956Ubiquitin
IPR029071Ubiquitin-related domain

No MapMan annotations defined for this gene.