Gene: ENSG00000169896 (Homo sapiens)

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Gene Identifier
ENSG00000169896
Transcript Identifier
ENST00000544665
Gene Type
Coding gene
Location
16 : 31260065-31331707 : positive

Family Information

Homologous gene family
HOM03P002672
(35 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P014730
(6 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
integrin, alpha M (complement component 3 receptor 3 subunit)

Identifiers

Type Value
pidENSP00000441691
HGNC6149
UniprotP11215

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002224
TAS
Genome Projecttoll-like receptor signaling pathway
GO:0002523
IEA
Genome Projectleukocyte migration involved in inflammatory response
GO:0007155
TAS, IEA
Genome Projectcell adhesion
GO:0007159
IEA
Genome Projectleukocyte cell-cell adhesion
GO:0007229
IEA
Genome Projectintegrin-mediated signaling pathway
GO:0007596
TAS
Genome Projectblood coagulation
GO:0010668
IEP
Genome Projectectodermal cell differentiation
GO:0014005
IEA
Genome Projectmicroglia development
GO:0016337
IEA
Genome Projectsingle organismal cell-cell adhesion
GO:0030198
TAS
Genome Projectextracellular matrix organization
GO:0030593
IEA
Genome Projectneutrophil chemotaxis
GO:0034142
TAS
Genome Projecttoll-like receptor 4 signaling pathway
GO:0045087
TAS
Genome Projectinnate immune response
GO:0045123
IEA
Genome Projectcellular extravasation
GO:0050798
IEA
Genome Projectactivated T cell proliferation
GO:0050900
TAS
Genome Projectleukocyte migration

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001846
IEA
Genome Projectopsonin binding
GO:0001948
IPI
Genome Projectglycoprotein binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008201
IEA
Genome Projectheparin binding
GO:0043395
IEA
Genome Projectheparan sulfate proteoglycan binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005615
IDA
Genome Projectextracellular space
GO:0005634
IEA
Genome Projectnucleus
GO:0005886
TAS
Genome Projectplasma membrane
GO:0008305
TAS, IEA
Genome Projectintegrin complex
GO:0009897
IEA
Genome Projectexternal side of plasma membrane
GO:0009986
IDA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000413Integrin alpha chain
IPR002035von Willebrand factor, type A
IPR013517FG-GAP repeat
IPR013519Integrin alpha beta-propellor
IPR013649Integrin alpha-2
IPR018184Integrin alpha chain, C-terminal cytoplasmic region, conserved site

No MapMan annotations defined for this gene.