Gene: ENSG00000169429 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000169429
Transcript Identifier
ENST00000307407
Gene Type
Coding gene
Location
4 : 73740659-73742464 : positive

Family Information

Homologous gene family
HOM03P006025
(15 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
chemokine (C-X-C motif) ligand 8

Identifiers

Type Value
pidENSP00000306512
HGNC6025
UniprotP10145
UniprotA0A024RDA5

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006935
TAS, IEA
Genome Projectchemotaxis
GO:0006955
IBA
IEA
Genome Projectimmune response
GO:0030593
IGI
IEA
Genome Projectneutrophil chemotaxis
GO:0042119
TAS, IEA
Genome Projectneutrophil activation
GO:0001525
TAS
Genome Projectangiogenesis
GO:0002237
IDA
Genome Projectresponse to molecule of bacterial origin
GO:0006928
TAS
Genome Projectmovement of cell or subcellular component
GO:0006954
TAS, IEA
Genome Projectinflammatory response
GO:0007050
IDA
Genome Projectcell cycle arrest
GO:0007165
TAS
Genome Projectsignal transduction
GO:0007186
TAS
Genome ProjectG-protein coupled receptor signaling pathway
GO:0008285
TAS
Genome Projectnegative regulation of cell proliferation
GO:0019722
TAS
Genome Projectcalcium-mediated signaling
GO:0030155
IDA
Genome Projectregulation of cell adhesion
GO:0030968
TAS
Genome Projectendoplasmic reticulum unfolded protein response
GO:0031623
IDA
Genome Projectreceptor internalization
GO:0034976
IDA
Genome Projectresponse to endoplasmic reticulum stress
GO:0035556
IDA
Genome Projectintracellular signal transduction
GO:0036499
TAS
Genome ProjectPERK-mediated unfolded protein response
GO:0044267
TAS
Genome Projectcellular protein metabolic process
GO:0044344
IEP
Genome Projectcellular response to fibroblast growth factor stimulus
GO:0045091
IDA
Genome Projectregulation of single stranded viral RNA replication via double stranded DNA intermediate
GO:0045744
IDA
Genome Projectnegative regulation of G-protein coupled receptor protein signaling pathway
GO:0045766
IDA
Genome Projectpositive regulation of angiogenesis
GO:0048566
IEP
Genome Projectembryonic digestive tract development
GO:0050930
IGI
Genome Projectinduction of positive chemotaxis
GO:0070098
IBA
Genome Projectchemokine-mediated signaling pathway
GO:0071222
IDA
Genome Projectcellular response to lipopolysaccharide
GO:0071347
IEP
Genome Projectcellular response to interleukin-1
GO:0071356
IEP
Genome Projectcellular response to tumor necrosis factor
GO:0090023
TAS
Genome Projectpositive regulation of neutrophil chemotaxis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005125
IEA
Genome Projectcytokine activity
GO:0005153
IPI
IEA
Genome Projectinterleukin-8 receptor binding
GO:0008009
TAS, IEA
Genome Projectchemokine activity
GO:0005515
IPI
Genome Projectprotein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS, IEA
Genome Projectextracellular region
GO:0005615
TAS, IEA
Genome Projectextracellular space
GO:0005622
IDA
TAS
Genome Projectintracellular

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001089CXC chemokine
IPR001811Chemokine interleukin-8-like domain
IPR018048CXC chemokine, conserved site
IPR028469Interleukin-8

No MapMan annotations defined for this gene.