Gene: ENSG00000169398 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000169398
Transcript Identifier
ENST00000519419
Gene Type
Coding gene
Location
8 : 140659466-140920913 : negative

Family Information

Homologous gene family
HOM03P000004
(1817 genes in 37 species)
specific family
Orthologous gene family
ORTHO03P015372
(6 genes in 4 species)
specific family

Descriptions

gene_descr
protein tyrosine kinase 2

Identifiers

Type Value
pidENSP00000429129
HGNC9611
UniprotE7ESA6

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006468
IEA
Genome Projectprotein phosphorylation
GO:0007010
IBA
Genome Projectcytoskeleton organization
GO:0007155
IBA
Genome Projectcell adhesion
GO:0007172
IEA
Genome Projectsignal complex assembly
GO:0007173
IBA
Genome Projectepidermal growth factor receptor signaling pathway
GO:0016310
IEA
Genome Projectphosphorylation
GO:0016477
IBA
Genome Projectcell migration
GO:0030154
IBA
Genome Projectcell differentiation
GO:0038083
IBA
Genome Projectpeptidyl-tyrosine autophosphorylation
GO:0045087
IBA
Genome Projectinnate immune response

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004713
IEA
Genome Projectprotein tyrosine kinase activity
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0005102
IBA
Genome Projectreceptor binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005925
IDA
IEA
Genome Projectfocal adhesion
GO:0031234
IBA
Genome Projectextrinsic component of cytoplasmic side of plasma membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000299FERM domain
IPR000719Protein kinase domain
IPR001245Serine-threonine/tyrosine-protein kinase catalytic domain
IPR005189Focal adhesion kinase, targeting (FAT) domain
IPR008266Tyrosine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR017441Protein kinase, ATP binding site
IPR019748FERM central domain
IPR019749Band 4.1 domain
IPR020635Tyrosine-protein kinase, catalytic domain
IPR029071Ubiquitin-related domain

No MapMan annotations defined for this gene.