Gene: ENSG00000169248 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000169248
Transcript Identifier
ENST00000503860
Gene Type
Coding gene
Location
4 : 76034793-76035987 : negative

Family Information

Homologous gene family
HOM03P006025
(15 genes in 2 species)
specific family
Orthologous gene family
ORTHO03P031011
(3 genes in 1 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
chemokine (C-X-C motif) ligand 11

Identifiers

Type Value
pidENSP00000425819
HGNC10638
UniprotO14625

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002690
IBA
Genome Projectpositive regulation of leukocyte chemotaxis
GO:0006935
IDA
TAS, IEA
Genome Projectchemotaxis
GO:0006954
TAS, IEA
Genome Projectinflammatory response
GO:0006955
IBA
IEA
Genome Projectimmune response
GO:0007165
TAS
Genome Projectsignal transduction
GO:0007186
IBA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007267
TAS
Genome Projectcell-cell signaling
GO:0010818
IMP
Genome ProjectT cell chemotaxis
GO:0030816
IDA
Genome Projectpositive regulation of cAMP metabolic process
GO:0032496
IBA
Genome Projectresponse to lipopolysaccharide
GO:0042127
IMP
Genome Projectregulation of cell proliferation
GO:0043950
IDA
Genome Projectpositive regulation of cAMP-mediated signaling
GO:0051281
IDA
Genome Projectpositive regulation of release of sequestered calcium ion into cytosol
GO:0070098
IMP
Genome Projectchemokine-mediated signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005125
IEA
Genome Projectcytokine activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008009
IDA
TAS, IEA
Genome Projectchemokine activity
GO:0008201
IMP
Genome Projectheparin binding
GO:0048248
IDA
Genome ProjectCXCR3 chemokine receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS, IEA
Genome Projectextracellular region
GO:0005615
IBA
IEA
Genome Projectextracellular space

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001089CXC chemokine
IPR001811Chemokine interleukin-8-like domain
IPR018048CXC chemokine, conserved site
IPR027221CXC chemokine 11

No MapMan annotations defined for this gene.