Gene: ENSG00000168918 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000168918
Transcript Identifier
ENST00000445964
Gene Type
Coding gene
Location
2 : 233060479-233206708 : positive

Family Information

Homologous gene family
HOM03P000237
(152 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P024247
(4 genes in 3 species)
specific family

Descriptions

gene_descr
inositol polyphosphate-5-phosphatase, 145kDa

Identifiers

Type Value
pidENSP00000405338
HGNC6079
UniprotQ92835

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002376
IEA
Genome Projectimmune system process
GO:0006470
TAS, IEA
Genome Projectprotein dephosphorylation
GO:0006644
TAS
Genome Projectphospholipid metabolic process
GO:0006661
TAS
Genome Projectphosphatidylinositol biosynthetic process
GO:0006796
TAS
Genome Projectphosphate-containing compound metabolic process
GO:0006915
IEA
Genome Projectapoptotic process
GO:0007165
TAS
Genome Projectsignal transduction
GO:0007596
TAS
Genome Projectblood coagulation
GO:0008285
IEA
Genome Projectnegative regulation of cell proliferation
GO:0008340
IEA
Genome Projectdetermination of adult lifespan
GO:0009968
IEA
Genome Projectnegative regulation of signal transduction
GO:0016064
IEA
Genome Projectimmunoglobulin mediated immune response
GO:0030853
IEA
Genome Projectnegative regulation of granulocyte differentiation
GO:0030889
IEA
Genome Projectnegative regulation of B cell proliferation
GO:0035556
IEA
Genome Projectintracellular signal transduction
GO:0043065
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043647
TAS
Genome Projectinositol phosphate metabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0045409
IEA
Genome Projectnegative regulation of interleukin-6 biosynthetic process
GO:0045579
IEA
Genome Projectpositive regulation of B cell differentiation
GO:0045621
IEA
Genome Projectpositive regulation of lymphocyte differentiation
GO:0045648
IEA
Genome Projectpositive regulation of erythrocyte differentiation
GO:0045656
IEA
Genome Projectnegative regulation of monocyte differentiation
GO:0045659
IEA
Genome Projectnegative regulation of neutrophil differentiation
GO:0045671
IEA
Genome Projectnegative regulation of osteoclast differentiation
GO:0045779
IEA
Genome Projectnegative regulation of bone resorption
GO:0046856
IEA
Genome Projectphosphatidylinositol dephosphorylation
GO:0050777
IEA
Genome Projectnegative regulation of immune response
GO:0050852
TAS
Genome ProjectT cell receptor signaling pathway
GO:0050869
IEA
Genome Projectnegative regulation of B cell activation
GO:0050900
TAS
Genome Projectleukocyte migration

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004445
TAS, IEA
Genome Projectinositol-polyphosphate 5-phosphatase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0017124
IEA
Genome ProjectSH3 domain binding
GO:0034594
IEA
Genome Projectphosphatidylinositol trisphosphate phosphatase activity
GO:0051425
IEA
Genome ProjectPTB domain binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0016020
IEA
Genome Projectmembrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000300Inositol polyphosphate-related phosphatase
IPR000980SH2 domain
IPR005135Endonuclease/exonuclease/phosphatase

No MapMan annotations defined for this gene.