Gene: ENSG00000168539 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000168539
Transcript Identifier
ENST00000306960
Gene Type
Coding gene
Location
11 : 62909718-62911100 : negative

Family Information

Homologous gene family
HOM03P000241
(150 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P071796
(2 genes in 2 species)
specific family

Descriptions

gene_descr
cholinergic receptor, muscarinic 1

Identifiers

Type Value
pidENSP00000306490
HGNC1950
UniprotP11229
UniprotQ53XZ3

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006464
TAS
Genome Projectcellular protein modification process
GO:0007165
TAS, IEA
Genome Projectsignal transduction
GO:0007186
TAS, IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007197
IBA
Genome Projectadenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway
GO:0007205
TAS
Genome Projectprotein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007207
TAS
Genome Projectphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
GO:0007213
ISS
TAS, IEA
Genome ProjectG-protein coupled acetylcholine receptor signaling pathway
GO:0007271
IBA
Genome Projectsynaptic transmission, cholinergic
GO:0007274
IEA
Genome Projectneuromuscular synaptic transmission
GO:0007399
TAS
Genome Projectnervous system development
GO:0007603
ISS
Genome Projectphototransduction, visible light
GO:0007606
IBA
Genome Projectsensory perception of chemical stimulus
GO:0008283
TAS
Genome Projectcell proliferation
GO:0008284
TAS
Genome Projectpositive regulation of cell proliferation
GO:0009649
ISS
Genome Projectentrainment of circadian clock
GO:0040012
IEA
Genome Projectregulation of locomotion
GO:0043270
IGI
Genome Projectpositive regulation of ion transport
GO:0046541
IEA
Genome Projectsaliva secretion
GO:0050890
IEA
Genome Projectcognition
GO:0090316
IEA
Genome Projectpositive regulation of intracellular protein transport
GO:0010579
IBA
Genome Projectpositive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004435
TAS
Genome Projectphosphatidylinositol phospholipase C activity
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0008144
IEA
Genome Projectdrug binding
GO:0016907
TAS, IEA
Genome ProjectG-protein coupled acetylcholine receptor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005887
TAS, IEA
Genome Projectintegral component of plasma membrane
GO:0014069
IEA
Genome Projectpostsynaptic density
GO:0016020
TAS, IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030054
IEA
Genome Projectcell junction
GO:0030425
IEA
Genome Projectdendrite
GO:0032279
IEA
Genome Projectasymmetric synapse
GO:0043679
IEA
Genome Projectaxon terminus
GO:0045202
IBA
IEA
Genome Projectsynapse
GO:0045211
IEA
Genome Projectpostsynaptic membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000276G protein-coupled receptor, rhodopsin-like
IPR000995Muscarinic acetylcholine receptor family
IPR002228Muscarinic acetylcholine receptor M1
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.