Gene: ENSG00000168398 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000168398
Transcript Identifier
ENST00000554311
Gene Type
Coding gene
Location
14 : 96237108-96241504 : positive

Family Information

Homologous gene family
HOM03P000080
(330 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P069413
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
bradykinin receptor B2

Identifiers

Type Value
pidENSP00000450482
HGNC1030
UniprotP30411

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002438
IEA
Genome Projectacute inflammatory response to antigenic stimulus
GO:0006939
IC, IEA
Genome Projectsmooth muscle contraction
GO:0006950
IEA
Genome Projectresponse to stress
GO:0006954
IC
Genome Projectinflammatory response
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007166
TAS
Genome Projectcell surface receptor signaling pathway
GO:0007169
TAS
Genome Projecttransmembrane receptor protein tyrosine kinase signaling pathway
GO:0007186
TAS, IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007204
TAS, IEA
Genome Projectpositive regulation of cytosolic calcium ion concentration
GO:0008015
NAS
Genome Projectblood circulation
GO:0008285
IEA
Genome Projectnegative regulation of cell proliferation
GO:0009651
IEA
Genome Projectresponse to salt stress
GO:0019229
IC
Genome Projectregulation of vasoconstriction
GO:0033137
IEA
Genome Projectnegative regulation of peptidyl-serine phosphorylation
GO:0035633
IEA
Genome Projectmaintenance of blood-brain barrier
GO:0042310
IEA
Genome Projectvasoconstriction
GO:0042311
IEA
Genome Projectvasodilation
GO:0042493
IEA
Genome Projectresponse to drug
GO:0043114
IC
Genome Projectregulation of vascular permeability
GO:0045776
IEA
Genome Projectnegative regulation of blood pressure
GO:0050482
IDA
Genome Projectarachidonic acid secretion
GO:0071456
IEA
Genome Projectcellular response to hypoxia
GO:1902219
IEA
Genome Projectnegative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
GO:1902239
IEA
Genome Projectnegative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002020
IPI
Genome Projectprotease binding
GO:0004435
TAS
Genome Projectphosphatidylinositol phospholipase C activity
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0004947
IDA
TAS, IEA
Genome Projectbradykinin receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0031698
IEA
Genome Projectbeta-2 adrenergic receptor binding
GO:0031702
IPI
Genome Projecttype 1 angiotensin receptor binding
GO:0046982
IPI
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005768
IDA
Genome Projectendosome
GO:0005829
TAS, IEA
Genome Projectcytosol
GO:0005886
IDA
TAS, IEA
Genome Projectplasma membrane
GO:0005887
TAS
Genome Projectintegral component of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000276G protein-coupled receptor, rhodopsin-like
IPR000496Bradykinin receptor family
IPR001504Bradykinin receptor B2
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.