Gene: ENSG00000168291 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000168291
Transcript Identifier
ENST00000302746
Gene Type
Coding gene
Location
3 : 58428034-58433809 : negative

Family Information

Homologous gene family
HOM03P000399
(112 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000694
(45 genes in 38 species)
specific family

Descriptions

gene_descr
pyruvate dehydrogenase (lipoamide) beta

Identifiers

Type Value
pidENSP00000307241
HGNC8808
UniprotP11177

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005975
IEA
Genome Projectcarbohydrate metabolic process
GO:0006006
IEA
Genome Projectglucose metabolic process
GO:0006086
IDA
IEA
Genome Projectacetyl-CoA biosynthetic process from pyruvate
GO:0006090
TAS
Genome Projectpyruvate metabolic process
GO:0006099
IDA
TAS, IEA
Genome Projecttricarboxylic acid cycle
GO:0008152
IEA
Genome Projectmetabolic process
GO:0010510
TAS
Genome Projectregulation of acetyl-CoA biosynthetic process from pyruvate
GO:0044237
TAS
Genome Projectcellular metabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0055114
IEA
Genome Projectoxidation-reduction process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003824
IEA
Genome Projectcatalytic activity
GO:0004738
IDA
Genome Projectpyruvate dehydrogenase activity
GO:0004739
TAS, IEA
Genome Projectpyruvate dehydrogenase (acetyl-transferring) activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0016491
IEA
Genome Projectoxidoreductase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
Genome Projectnucleus
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005739
IDA
IEA
Genome Projectmitochondrion
GO:0005759
TAS, IEA
Genome Projectmitochondrial matrix
GO:0045254
IDA
Genome Projectpyruvate dehydrogenase complex
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR005475Transketolase-like, pyrimidine-binding domain
IPR009014Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II
IPR027110Pyruvate dehydrogenase E1 component subunit beta
IPR029061Thiamin diphosphate-binding fold

No MapMan annotations defined for this gene.