Gene: ENSG00000168036 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000168036
Transcript Identifier
ENST00000396185
Gene Type
Coding gene
Location
3 : 41224069-41239342 : positive

Family Information

Homologous gene family
HOM03P011977
(7 genes in 4 species)
specific family

Descriptions

gene_descr
catenin (cadherin-associated protein), beta 1, 88kDa

Identifiers

Type Value
pidENSP00000379488
HGNC2514
UniprotP35222
UniprotA0A024R2Q3

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0000578
IEA
Genome Projectembryonic axis specification
GO:0000904
IEA
Genome Projectcell morphogenesis involved in differentiation
GO:0001501
IEA
Genome Projectskeletal system development
GO:0001569
IC, IEA
Genome Projectpatterning of blood vessels
GO:0001570
IEA
Genome Projectvasculogenesis
GO:0001658
IEA
Genome Projectbranching involved in ureteric bud morphogenesis
GO:0001701
IEA
Genome Projectin utero embryonic development
GO:0001702
IEA
Genome Projectgastrulation with mouth forming second
GO:0001706
IEA
Genome Projectendoderm formation
GO:0001708
IEA
Genome Projectcell fate specification
GO:0001709
IEA
Genome Projectcell fate determination
GO:0001711
IEA
Genome Projectendodermal cell fate commitment
GO:0001764
IEA
Genome Projectneuron migration
GO:0001822
IEA
Genome Projectkidney development
GO:0001840
IEA
Genome Projectneural plate development
GO:0001944
IEA
Genome Projectvasculature development
GO:0002052
ISS
IEA
Genome Projectpositive regulation of neuroblast proliferation
GO:0002053
IEA
Genome Projectpositive regulation of mesenchymal cell proliferation
GO:0002089
IEA
Genome Projectlens morphogenesis in camera-type eye
GO:0003266
IEA
Genome Projectregulation of secondary heart field cardioblast proliferation
GO:0003337
IEA
Genome Projectmesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0003338
IEA
Genome Projectmetanephros morphogenesis
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IEA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0007160
IEA
Genome Projectcell-matrix adhesion
GO:0007268
IEA
Genome Projectsynaptic transmission
GO:0007398
IEA
Genome Projectectoderm development
GO:0007403
IEA
Genome Projectglial cell fate determination
GO:0007507
IEA
Genome Projectheart development
GO:0008283
IEA
Genome Projectcell proliferation
GO:0008284
IEA
Genome Projectpositive regulation of cell proliferation
GO:0009948
IEA
Genome Projectanterior/posterior axis specification
GO:0009950
IEA
Genome Projectdorsal/ventral axis specification
GO:0009953
IEA
Genome Projectdorsal/ventral pattern formation
GO:0009954
IEA
Genome Projectproximal/distal pattern formation
GO:0009987
IEA
Genome Projectcellular process
GO:0010468
IEA
Genome Projectregulation of gene expression
GO:0010628
IEA
Genome Projectpositive regulation of gene expression
GO:0016055
IDA
IEA
Genome ProjectWnt signaling pathway
GO:0016331
IEA
Genome Projectmorphogenesis of embryonic epithelium
GO:0016337
IMP
IEA
Genome Projectsingle organismal cell-cell adhesion
GO:0021819
IEA
Genome Projectlayer formation in cerebral cortex
GO:0022009
IEA
Genome Projectcentral nervous system vasculogenesis
GO:0022405
IEA
Genome Projecthair cycle process
GO:0030097
IEA
Genome Projecthemopoiesis
GO:0030154
IEA
Genome Projectcell differentiation
GO:0030217
IEA
Genome ProjectT cell differentiation
GO:0030316
IEA
Genome Projectosteoclast differentiation
GO:0030324
IEA
Genome Projectlung development
GO:0030539
IEA
Genome Projectmale genitalia development
GO:0030856
IEA
Genome Projectregulation of epithelial cell differentiation
GO:0030858
IEA
Genome Projectpositive regulation of epithelial cell differentiation
GO:0030900
IEA
Genome Projectforebrain development
GO:0031016
IEA
Genome Projectpancreas development
GO:0031069
IEA
Genome Projecthair follicle morphogenesis
GO:0031641
IEA
Genome Projectregulation of myelination
GO:0032212
IEA
Genome Projectpositive regulation of telomere maintenance via telomerase
GO:0032331
IEA
Genome Projectnegative regulation of chondrocyte differentiation
GO:0033077
IEA
Genome ProjectT cell differentiation in thymus
GO:0034332
IEA
Genome Projectadherens junction organization
GO:0034333
IMP
IEA
Genome Projectadherens junction assembly
GO:0034613
IEA
Genome Projectcellular protein localization
GO:0035050
IEA
Genome Projectembryonic heart tube development
GO:0035112
IEA
Genome Projectgenitalia morphogenesis
GO:0035115
IEA
Genome Projectembryonic forelimb morphogenesis
GO:0035116
IEA
Genome Projectembryonic hindlimb morphogenesis
GO:0036023
ISS
IEA
Genome Projectembryonic skeletal limb joint morphogenesis
GO:0042127
IEA
Genome Projectregulation of cell proliferation
GO:0042129
IEA
Genome Projectregulation of T cell proliferation
GO:0042475
IEA
Genome Projectodontogenesis of dentin-containing tooth
GO:0042733
IEA
Genome Projectembryonic digit morphogenesis
GO:0042981
IEA
Genome Projectregulation of apoptotic process
GO:0043123
IEA
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043410
IEA
Genome Projectpositive regulation of MAPK cascade
GO:0043588
IEA
Genome Projectskin development
GO:0045453
IEA
Genome Projectbone resorption
GO:0045595
IEA
Genome Projectregulation of cell differentiation
GO:0045596
IEA
Genome Projectnegative regulation of cell differentiation
GO:0045603
IEA
Genome Projectpositive regulation of endothelial cell differentiation
GO:0045667
IEA
Genome Projectregulation of osteoblast differentiation
GO:0045669
IEA
Genome Projectpositive regulation of osteoblast differentiation
GO:0045670
IEA
Genome Projectregulation of osteoclast differentiation
GO:0045671
IEA
Genome Projectnegative regulation of osteoclast differentiation
GO:0045743
IEA
Genome Projectpositive regulation of fibroblast growth factor receptor signaling pathway
GO:0045892
IMP
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
IDA, IMP
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045976
ISS
IEA
Genome Projectnegative regulation of mitotic cell cycle, embryonic
GO:0048096
IEA
Genome Projectchromatin-mediated maintenance of transcription
GO:0048469
IEA
Genome Projectcell maturation
GO:0048489
IEA
Genome Projectsynaptic vesicle transport
GO:0048513
IEA
Genome Projectorgan development
GO:0048538
IEA
Genome Projectthymus development
GO:0048599
IEA
Genome Projectoocyte development
GO:0048617
IEA
Genome Projectembryonic foregut morphogenesis
GO:0048643
IEA
Genome Projectpositive regulation of skeletal muscle tissue development
GO:0048715
IEA
Genome Projectnegative regulation of oligodendrocyte differentiation
GO:0050808
IEA
Genome Projectsynapse organization
GO:0051145
IEA
Genome Projectsmooth muscle cell differentiation
GO:0051973
IEA
Genome Projectpositive regulation of telomerase activity
GO:0060066
IEA
Genome Projectoviduct development
GO:0060070
IDA
IEA
Genome Projectcanonical Wnt signaling pathway
GO:0060173
IEA
Genome Projectlimb development
GO:0060439
IEA
Genome Projecttrachea morphogenesis
GO:0060440
IEA
Genome Projecttrachea formation
GO:0060441
IEA
Genome Projectepithelial tube branching involved in lung morphogenesis
GO:0060479
IEA
Genome Projectlung cell differentiation
GO:0060484
IEA
Genome Projectlung-associated mesenchyme development
GO:0060492
IEA
Genome Projectlung induction
GO:0060742
IEA
Genome Projectepithelial cell differentiation involved in prostate gland development
GO:0060769
IEA
Genome Projectpositive regulation of epithelial cell proliferation involved in prostate gland development
GO:0060789
IEA
Genome Projecthair follicle placode formation
GO:0060916
IEA
Genome Projectmesenchymal cell proliferation involved in lung development
GO:0061047
IEA
Genome Projectpositive regulation of branching involved in lung morphogenesis
GO:0061198
IEA
Genome Projectfungiform papilla formation
GO:0061324
ISS
IEA
Genome Projectcanonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation
GO:0061549
ISS
IEA
Genome Projectsympathetic ganglion development
GO:0070602
IMP
IEA
Genome Projectregulation of centromeric sister chromatid cohesion
GO:0071407
IEA
Genome Projectcellular response to organic cyclic compound
GO:0072001
IEA
Genome Projectrenal system development
GO:0072033
IEA
Genome Projectrenal vesicle formation
GO:0072053
IEA
Genome Projectrenal inner medulla development
GO:0072054
IEA
Genome Projectrenal outer medulla development
GO:0072079
IEA
Genome Projectnephron tubule formation
GO:0072182
ISS
IEA
Genome Projectregulation of nephron tubule epithelial cell differentiation
GO:1901215
IEA
Genome Projectnegative regulation of neuron death
GO:2000017
IEA
Genome Projectpositive regulation of determination of dorsal identity
GO:2001234
IEA
Genome Projectnegative regulation of apoptotic signaling pathway
GO:0001837
TAS
Genome Projectepithelial to mesenchymal transition
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006915
TAS
Genome Projectapoptotic process
GO:0006921
TAS
Genome Projectcellular component disassembly involved in execution phase of apoptosis
GO:0007155
IMP
IEA
Genome Projectcell adhesion
GO:0007264
TAS
Genome Projectsmall GTPase mediated signal transduction
GO:0007399
IEA
Genome Projectnervous system development
GO:0008285
IDA
Genome Projectnegative regulation of cell proliferation
GO:0010718
IGI
Genome Projectpositive regulation of epithelial to mesenchymal transition
GO:0010909
IMP
Genome Projectpositive regulation of heparan sulfate proteoglycan biosynthetic process
GO:0012501
TAS
Genome Projectprogrammed cell death
GO:0019827
TAS
Genome Projectstem cell population maintenance
GO:0030521
NAS
Genome Projectandrogen receptor signaling pathway
GO:0030997
IDA
Genome Projectregulation of centriole-centriole cohesion
GO:0032355
IDA
Genome Projectresponse to estradiol
GO:0032481
TAS
Genome Projectpositive regulation of type I interferon production
GO:0033234
IDA
Genome Projectnegative regulation of protein sumoylation
GO:0034394
IMP
Genome Projectprotein localization to cell surface
GO:0035315
TAS
Genome Projecthair cell differentiation
GO:0042493
IEP
Genome Projectresponse to drug
GO:0042659
IBA
Genome Projectregulation of cell fate specification
GO:0042692
TAS
Genome Projectmuscle cell differentiation
GO:0043065
IDA
Genome Projectpositive regulation of apoptotic process
GO:0044334
IMP
Genome Projectcanonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition
GO:0044336
IMP
Genome Projectcanonical Wnt signaling pathway involved in negative regulation of apoptotic process
GO:0045087
TAS
Genome Projectinnate immune response
GO:0045765
TAS
Genome Projectregulation of angiogenesis
GO:0045944
IDA, IMP
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048145
TAS
Genome Projectregulation of fibroblast proliferation
GO:0048660
IMP
Genome Projectregulation of smooth muscle cell proliferation
GO:0051149
TAS
Genome Projectpositive regulation of muscle cell differentiation
GO:0051571
IC
Genome Projectpositive regulation of histone H3-K4 methylation
GO:0061154
IMP
Genome Projectendothelial tube morphogenesis
GO:0071363
IMP
Genome Projectcellular response to growth factor stimulus
GO:0071681
IDA
Genome Projectcellular response to indole-3-methanol
GO:0090263
TAS
Genome Projectpositive regulation of canonical Wnt signaling pathway
GO:0090279
IDA
Genome Projectregulation of calcium ion import
GO:2000008
IDA
Genome Projectregulation of protein localization to cell surface
GO:2000144
IC
Genome Projectpositive regulation of DNA-templated transcription, initiation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003682
IEA
Genome Projectchromatin binding
GO:0003690
IEA
Genome Projectdouble-stranded DNA binding
GO:0003700
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003713
IDA, IMP
IEA
Genome Projecttranscription coactivator activity
GO:0004871
NAS, IEA
Genome Projectsignal transducer activity
GO:0008134
IPI
TAS, IEA
Genome Projecttranscription factor binding
GO:0019903
IPI
IEA
Genome Projectprotein phosphatase binding
GO:0035257
IPI
TAS, IEA
Genome Projectnuclear hormone receptor binding
GO:0044212
IDA
IEA
Genome Projecttranscription regulatory region DNA binding
GO:0045294
IPI
IEA
Genome Projectalpha-catenin binding
GO:0070491
IEA
Genome Projectrepressing transcription factor binding
GO:1990188
IDA
IEA
Genome Projecteuchromatin binding
GO:0001102
IPI
Genome ProjectRNA polymerase II activating transcription factor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008022
IPI
Genome Projectprotein C-terminus binding
GO:0019899
IPI
Genome Projectenzyme binding
GO:0019900
IPI
Genome Projectkinase binding
GO:0030331
IPI
Genome Projectestrogen receptor binding
GO:0044325
IPI
Genome Projection channel binding
GO:0045296
IPI
Genome Projectcadherin binding
GO:0046332
IPI
Genome ProjectSMAD binding
GO:0050681
NAS
Genome Projectandrogen receptor binding
GO:0070411
IPI
Genome ProjectI-SMAD binding
GO:0070412
IPI
Genome ProjectR-SMAD binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005667
IDA
IEA
Genome Projecttranscription factor complex
GO:0005719
IDA
IEA
Genome Projectnuclear euchromatin
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005813
IDA
IEA
Genome Projectcentrosome
GO:0005829
IDA
TAS, IEA
Genome Projectcytosol
GO:0005886
IDA
IEA
Genome Projectplasma membrane
GO:0005911
IDA
IEA
Genome Projectcell-cell junction
GO:0005912
IDA
IEA
Genome Projectadherens junction
GO:0005913
IDA
IEA
Genome Projectcell-cell adherens junction
GO:0005916
IEA
Genome Projectfascia adherens
GO:0005923
IEA
Genome Projectbicellular tight junction
GO:0014704
IEA
Genome Projectintercalated disc
GO:0016020
ISS
IEA
Genome Projectmembrane
GO:0016323
IDA
IEA
Genome Projectbasolateral plasma membrane
GO:0030018
IEA
Genome ProjectZ disc
GO:0030027
IEA
Genome Projectlamellipodium
GO:0031253
IEA
Genome Projectcell projection membrane
GO:0031528
IEA
Genome Projectmicrovillus membrane
GO:0034750
IEA
Genome ProjectScrib-APC-beta-catenin complex
GO:0043296
IEA
Genome Projectapical junction complex
GO:0044798
IEA
Genome Projectnuclear transcription factor complex
GO:0045177
IEA
Genome Projectapical part of cell
GO:0071664
IEA
Genome Projectcatenin-TCF7L2 complex
GO:0000922
IEA
Genome Projectspindle pole
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005815
IEA
Genome Projectmicrotubule organizing center
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005925
IDA
Genome Projectfocal adhesion
GO:0005938
IDA
Genome Projectcell cortex
GO:0016328
IDA
Genome Projectlateral plasma membrane
GO:0016342
IDA
Genome Projectcatenin complex
GO:0030054
IDA
TAS, IEA
Genome Projectcell junction
GO:0030877
IDA
Genome Projectbeta-catenin destruction complex
GO:0032993
IDA
Genome Projectprotein-DNA complex
GO:0043234
IDA
Genome Projectprotein complex
GO:0048471
IDA
Genome Projectperinuclear region of cytoplasm
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0070369
IDA
Genome Projectbeta-catenin-TCF7L2 complex
GO:0071944
IDA
Genome Projectcell periphery

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000225Armadillo
IPR011989Armadillo-like helical
IPR013284Beta-catenin
IPR016024Armadillo-type fold

No MapMan annotations defined for this gene.