Gene: ENSG00000167780 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000167780
Transcript Identifier
ENST00000301466
Gene Type
Coding gene
Location
12 : 53103578-53124123 : positive

Family Information

Homologous gene family
HOM03P001013
(61 genes in 32 species)
specific family
Orthologous gene family
ORTHO03P025260
(4 genes in 3 species)
specific family

Descriptions

gene_descr
sterol O-acyltransferase 2

Identifiers

Type Value
pidENSP00000301466
HGNC11178
UniprotO75908

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006629
IEA
Genome Projectlipid metabolic process
GO:0008202
IEA
Genome Projectsteroid metabolic process
GO:0008203
IDA
IEA
Genome Projectcholesterol metabolic process
GO:0010742
TAS
Genome Projectmacrophage derived foam cell differentiation
GO:0030299
IC
Genome Projectintestinal cholesterol absorption
GO:0033344
IMP
Genome Projectcholesterol efflux
GO:0034379
IMP
Genome Projectvery-low-density lipoprotein particle assembly
GO:0034435
IDA
IEA
Genome Projectcholesterol esterification
GO:0042632
TAS, IEA
Genome Projectcholesterol homeostasis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000062
IDA
Genome Projectfatty-acyl-CoA binding
GO:0004772
IEA
Genome Projectsterol O-acyltransferase activity
GO:0008374
IEA
Genome ProjectO-acyltransferase activity
GO:0015485
IDA
Genome Projectcholesterol binding
GO:0016740
IEA
Genome Projecttransferase activity
GO:0016746
TAS, IEA
Genome Projecttransferase activity, transferring acyl groups
GO:0034736
IDA
IEA
Genome Projectcholesterol O-acyltransferase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005783
IDA
IEA
Genome Projectendoplasmic reticulum
GO:0005789
IDA
IEA
Genome Projectendoplasmic reticulum membrane
GO:0005903
IDA
Genome Projectbrush border
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR004299Membrane bound O-acyl transferase, MBOAT
IPR014371Sterol O-acyltransferase, ACAT/DAG/ARE types
IPR030687Sterol O-acyltransferase, metazoa

No MapMan annotations defined for this gene.