Gene: ENSG00000167193 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000167193
Transcript Identifier
ENST00000300574
Gene Type
Coding gene
Location
17 : 1423513-1456117 : negative

Family Information

Homologous gene family
HOM03P013081
(6 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P042367
(3 genes in 3 species)
specific family

Descriptions

gene_descr
v-crk avian sarcoma virus CT10 oncogene homolog

Identifiers

Type Value
pidENSP00000300574
HGNC2362
UniprotP46108
UniprotL7RT18

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009967
IEA
Genome Projectpositive regulation of signal transduction
GO:0035020
IEA
Genome Projectregulation of Rac protein signal transduction
GO:0000186
TAS
Genome Projectactivation of MAPKK activity
GO:0006357
TAS
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0007596
TAS
Genome Projectblood coagulation
GO:0008286
TAS
Genome Projectinsulin receptor signaling pathway
GO:0030168
TAS
Genome Projectplatelet activation
GO:0032956
IDA
Genome Projectregulation of actin cytoskeleton organization
GO:0038096
TAS
Genome ProjectFc-gamma receptor signaling pathway involved in phagocytosis
GO:0043087
IDA
Genome Projectregulation of GTPase activity
GO:0045087
TAS
Genome Projectinnate immune response
GO:0048010
TAS
Genome Projectvascular endothelial growth factor receptor signaling pathway
GO:0048011
TAS
Genome Projectneurotrophin TRK receptor signaling pathway
GO:0048013
IDA
Genome Projectephrin receptor signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005070
IEA
Genome ProjectSH3/SH2 adaptor activity
GO:0019904
IEA
Genome Projectprotein domain specific binding
GO:0030674
IEA
Genome Projectprotein binding, bridging
GO:0045309
IEA
Genome Projectprotein phosphorylated amino acid binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0042169
IPI
Genome ProjectSH2 domain binding
GO:0046875
IPI
Genome Projectephrin receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0015629
IEA
Genome Projectactin cytoskeleton
GO:0005634
TAS
Genome Projectnucleus
GO:0005737
IC, IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0005886
IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000980SH2 domain
IPR001452SH3 domain
IPR011511Variant SH3 domain

No MapMan annotations defined for this gene.