Gene: ENSG00000167136 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000167136
Transcript Identifier
ENST00000372642
Gene Type
Coding gene
Location
9 : 128818685-128822610 : positive

Family Information

Homologous gene family
HOM03P002597
(36 genes in 28 species)
specific family
Orthologous gene family
ORTHO03P002846
(28 genes in 27 species)
specific family

Descriptions

gene_descr
endonuclease G

Identifiers

Type Value
pidENSP00000361725
HGNC3346
UniprotQ14249
UniprotE5KNL5

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001701
IEA
Genome Projectin utero embryonic development
GO:0006309
IBA
IEA
Genome Projectapoptotic DNA fragmentation
GO:0007568
IEA
Genome Projectaging
GO:0009612
IEA
Genome Projectresponse to mechanical stimulus
GO:0032355
IEA
Genome Projectresponse to estradiol
GO:0034599
IEA
Genome Projectcellular response to oxidative stress
GO:0034612
IEA
Genome Projectresponse to tumor necrosis factor
GO:0036475
IEA
Genome Projectneuron death in response to oxidative stress
GO:0043065
IEA
Genome Projectpositive regulation of apoptotic process
GO:0046677
IEA
Genome Projectresponse to antibiotic
GO:0071277
IEA
Genome Projectcellular response to calcium ion
GO:0071333
IEA
Genome Projectcellular response to glucose stimulus
GO:0071456
IEA
Genome Projectcellular response to hypoxia
GO:1901300
IEA
Genome Projectpositive regulation of hydrogen peroxide-mediated programmed cell death
GO:1902512
IEA
Genome Projectpositive regulation of apoptotic DNA fragmentation
GO:0006310
TAS
Genome ProjectDNA recombination

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003676
IEA
Genome Projectnucleic acid binding
GO:0004519
IEA
Genome Projectendonuclease activity
GO:0004536
IEA
Genome Projectdeoxyribonuclease activity
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0004518
IBA
IEA
Genome Projectnuclease activity
GO:0005515
IPI
Genome Projectprotein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0005739
IEA
Genome Projectmitochondrion
GO:0005829
IEA
Genome Projectcytosol
GO:0043204
IEA
Genome Projectperikaryon

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001604DNA/RNA non-specific endonuclease
IPR018524DNA/RNA non-specific endonuclease, active site
IPR020821Extracellular Endonuclease, subunit A

No MapMan annotations defined for this gene.