Gene: ENSG00000166501 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000166501
Transcript Identifier
ENST00000303531
Gene Type
Coding gene
Location
16 : 23836176-24214816 : positive

Family Information

Homologous gene family
HOM03P000015
(1237 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P005549
(15 genes in 6 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
protein kinase C, beta

Identifiers

Type Value
pidENSP00000305355
HGNC9395
UniprotP05771

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000278
TAS
Genome Projectmitotic cell cycle
GO:0002250
IEA
Genome Projectadaptive immune response
GO:0002376
IEA
Genome Projectimmune system process
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IMP
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0006468
TAS, IEA
Genome Projectprotein phosphorylation
GO:0006816
IEA
Genome Projectcalcium ion transport
GO:0006874
IEA
Genome Projectcellular calcium ion homeostasis
GO:0006915
IEA
Genome Projectapoptotic process
GO:0007077
TAS
Genome Projectmitotic nuclear envelope disassembly
GO:0007165
NAS
Genome Projectsignal transduction
GO:0007268
TAS
Genome Projectsynaptic transmission
GO:0007596
TAS
Genome Projectblood coagulation
GO:0010829
ISS
IEA
Genome Projectnegative regulation of glucose transport
GO:0016310
IEA
Genome Projectphosphorylation
GO:0016568
IEA
Genome Projectchromatin modification
GO:0030168
TAS
Genome Projectplatelet activation
GO:0030949
ISS
IEA
Genome Projectpositive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0035408
IDA
Genome Projecthistone H3-T6 phosphorylation
GO:0035556
IEA
Genome Projectintracellular signal transduction
GO:0042113
ISS
IEA
Genome ProjectB cell activation
GO:0042953
TAS
Genome Projectlipoprotein transport
GO:0043123
ISS
IEA
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045766
ISS
IEA
Genome Projectpositive regulation of angiogenesis
GO:0046627
ISS
Genome Projectnegative regulation of insulin receptor signaling pathway
GO:0048010
TAS
Genome Projectvascular endothelial growth factor receptor signaling pathway
GO:0050853
ISS
IEA
Genome ProjectB cell receptor signaling pathway
GO:0050861
ISS
IEA
Genome Projectpositive regulation of B cell receptor signaling pathway
GO:0051092
ISS
IEA
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0071322
IEA
Genome Projectcellular response to carbohydrate stimulus

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0003682
IDA
Genome Projectchromatin binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004674
EXP
TAS, IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004697
TAS, IEA
Genome Projectprotein kinase C activity
GO:0005080
IPI
Genome Projectprotein kinase C binding
GO:0005246
IEA
Genome Projectcalcium channel regulator activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0030374
IMP
Genome Projectligand-dependent nuclear receptor transcription coactivator activity
GO:0035403
IDA
Genome Projecthistone kinase activity (H3-T6 specific)
GO:0042393
IDA
Genome Projecthistone binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0050681
IDA
Genome Projectandrogen receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0005886
IDA
TAS
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000008C2 domain
IPR000719Protein kinase domain
IPR000961AGC-kinase, C-terminal
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR014375Protein kinase C, alpha/beta/gamma types
IPR017441Protein kinase, ATP binding site
IPR017892Protein kinase, C-terminal
IPR020454Diacylglycerol/phorbol-ester binding

No MapMan annotations defined for this gene.