Gene: ENSG00000165197 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000165197
Transcript Identifier
ENST00000297904
Gene Type
Coding gene
Location
X : 15346133-15383946 : negative

Family Information

Homologous gene family
HOM03P016811
(5 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
c-fos induced growth factor (vascular endothelial growth factor D)

Identifiers

Type Value
pidENSP00000297904
HGNC3708
UniprotO43915

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001525
IEA
Genome Projectangiogenesis
GO:0001666
IEA
Genome Projectresponse to hypoxia
GO:0002576
TAS
Genome Projectplatelet degranulation
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007596
TAS
Genome Projectblood coagulation
GO:0008283
IEA
Genome Projectcell proliferation
GO:0008284
TAS, IEA
Genome Projectpositive regulation of cell proliferation
GO:0030154
IEA
Genome Projectcell differentiation
GO:0030168
TAS
Genome Projectplatelet activation
GO:0030947
IEA
Genome Projectregulation of vascular endothelial growth factor receptor signaling pathway
GO:0032755
IEA
Genome Projectpositive regulation of interleukin-6 production
GO:0048010
TAS, IEA
Genome Projectvascular endothelial growth factor receptor signaling pathway
GO:0050918
IDA
Genome Projectpositive chemotaxis
GO:0050930
IDA
Genome Projectinduction of positive chemotaxis
GO:0051781
IEA
Genome Projectpositive regulation of cell division
GO:0060754
IDA
Genome Projectpositive regulation of mast cell chemotaxis
GO:0070555
IEA
Genome Projectresponse to interleukin-1

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005161
TAS
Genome Projectplatelet-derived growth factor receptor binding
GO:0005172
IPI
IEA
Genome Projectvascular endothelial growth factor receptor binding
GO:0008083
IEA
Genome Projectgrowth factor activity
GO:0042056
IDA
Genome Projectchemoattractant activity
GO:0042803
IEA
Genome Projectprotein homodimerization activity
GO:0043185
IEA
Genome Projectvascular endothelial growth factor receptor 3 binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS, IEA
Genome Projectextracellular region
GO:0005615
TAS, IEA
Genome Projectextracellular space
GO:0016020
IEA
Genome Projectmembrane
GO:0031093
TAS
Genome Projectplatelet alpha granule lumen

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000072PDGF/VEGF domain
IPR023581Platelet-derived growth factor, conserved site
IPR029034Cystine-knot cytokine

No MapMan annotations defined for this gene.