Gene: ENSG00000164741 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000164741
Transcript Identifier
ENST00000276297
Gene Type
Coding gene
Location
8 : 13085811-13500071 : negative

Family Information

Homologous gene family
HOM03P010967
(7 genes in 4 species)
specific family

Descriptions

gene_descr
DLC1 Rho GTPase activating protein

Identifiers

Type Value
pidENSP00000276297
HGNC2897
UniprotQ96QB1

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001843
ISS
IEA
Genome Projectneural tube closure
GO:0003007
ISS
IEA
Genome Projectheart morphogenesis
GO:0006915
IDA
Genome Projectapoptotic process
GO:0006919
IDA
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007264
TAS
Genome Projectsmall GTPase mediated signal transduction
GO:0008285
IDA, IMP
Genome Projectnegative regulation of cell proliferation
GO:0008360
IMP
Genome Projectregulation of cell shape
GO:0021575
ISS
IEA
Genome Projecthindbrain morphogenesis
GO:0030036
ISS
IEA
Genome Projectactin cytoskeleton organization
GO:0030336
IDA, IMP
Genome Projectnegative regulation of cell migration
GO:0030900
ISS
IEA
Genome Projectforebrain development
GO:0032956
IMP
Genome Projectregulation of actin cytoskeleton organization
GO:0035023
IEA
Genome Projectregulation of Rho protein signal transduction
GO:0035024
IMP
Genome Projectnegative regulation of Rho protein signal transduction
GO:0035307
IDA
Genome Projectpositive regulation of protein dephosphorylation
GO:0043547
IDA, IMP
Genome Projectpositive regulation of GTPase activity
GO:0048041
ISS
IEA
Genome Projectfocal adhesion assembly
GO:0051056
TAS
Genome Projectregulation of small GTPase mediated signal transduction
GO:0051497
IDA
Genome Projectnegative regulation of stress fiber assembly
GO:0051895
IDA
Genome Projectnegative regulation of focal adhesion assembly
GO:1900119
IDA
Genome Projectpositive regulation of execution phase of apoptosis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005096
IDA, IMP
Genome ProjectGTPase activator activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008289
IEA
Genome Projectlipid binding
GO:0042169
IPI
Genome ProjectSH2 domain binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
Genome Projectnucleus
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005829
IDA
TAS
Genome Projectcytosol
GO:0005901
IDA
Genome Projectcaveola
GO:0005925
IDA
IEA
Genome Projectfocal adhesion
GO:0016020
IEA
Genome Projectmembrane
GO:0030054
IEA
Genome Projectcell junction
GO:0030864
IDA
Genome Projectcortical actin cytoskeleton
GO:0032587
IDA
Genome Projectruffle membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000198Rho GTPase-activating protein domain
IPR001660Sterile alpha motif domain
IPR002913START domain
IPR008936Rho GTPase activation protein
IPR013761Sterile alpha motif/pointed domain
IPR023393START-like domain
IPR028854Rho GTPase-activating protein 7

No MapMan annotations defined for this gene.