Gene: ENSG00000164458 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000164458
Transcript Identifier
ENST00000296946
Gene Type
Coding gene
Location
6 : 166158315-166167591 : negative

Family Information

Homologous gene family
HOM03P001268
(54 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P075366
(2 genes in 2 species)
specific family

Descriptions

gene_descr
T, brachyury homolog (mouse)

Identifiers

Type Value
pidENSP00000296946
HGNC11515
UniprotO15178

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
ISS
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001570
IEA
Genome Projectvasculogenesis
GO:0001756
IEA
Genome Projectsomitogenesis
GO:0001839
IEA
Genome Projectneural plate morphogenesis
GO:0001843
IEA
Genome Projectneural tube closure
GO:0003007
IDA
Genome Projectheart morphogenesis
GO:0003257
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IEA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0007165
NAS
Genome Projectsignal transduction
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007341
IEA
Genome Projectpenetration of zona pellucida
GO:0007498
TAS, IEA
Genome Projectmesoderm development
GO:0007509
IEA
Genome Projectmesoderm migration involved in gastrulation
GO:0008284
IEA
Genome Projectpositive regulation of cell proliferation
GO:0008595
TAS
Genome Projectanterior/posterior axis specification, embryo
GO:0009653
IEA
Genome Projectanatomical structure morphogenesis
GO:0009952
IEA
Genome Projectanterior/posterior pattern specification
GO:0014028
IEA
Genome Projectnotochord formation
GO:0022414
IEA
Genome Projectreproductive process
GO:0023019
IEA
Genome Projectsignal transduction involved in regulation of gene expression
GO:0030509
IEA
Genome ProjectBMP signaling pathway
GO:0030903
IEA
Genome Projectnotochord development
GO:0036342
IEA
Genome Projectpost-anal tail morphogenesis
GO:0045944
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048706
IEA
Genome Projectembryonic skeletal system development
GO:0060070
IEA
Genome Projectcanonical Wnt signaling pathway
GO:0060349
IEA
Genome Projectbone morphogenesis
GO:0060395
IEA
Genome ProjectSMAD protein signal transduction
GO:0061371
IEA
Genome Projectdetermination of heart left/right asymmetry
GO:0071300
IEA
Genome Projectcellular response to retinoic acid
GO:0090009
NAS
Genome Projectprimitive streak formation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000978
ISS
IEA
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980
IDA
Genome ProjectRNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000981
IEA
Genome ProjectRNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0001085
ISS
IEA
Genome ProjectRNA polymerase II transcription factor binding
GO:0001102
IPI
Genome ProjectRNA polymerase II activating transcription factor binding
GO:0001191
ISS
IEA
Genome Projecttranscriptional repressor activity, RNA polymerase II transcription factor binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003700
NAS, IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003705
IDA
Genome Projecttranscription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000785
IEA
Genome Projectchromatin
GO:0000790
IDA
Genome Projectnuclear chromatin
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005737
IEA
Genome Projectcytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001699Transcription factor, T-box
IPR002070Transcription factor, Brachyury
IPR008967p53-like transcription factor, DNA-binding
IPR018186Transcription factor, T-box, conserved site

No MapMan annotations defined for this gene.