Gene: ENSG00000164418 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000164418
Transcript Identifier
ENST00000421544
Gene Type
Coding gene
Location
6 : 101399278-102068511 : positive

Family Information

Homologous gene family
HOM03P000932
(65 genes in 7 species)
specific family
Orthologous gene family
ORTHO03P002420
(30 genes in 4 species)
specific family

Descriptions

gene_descr
glutamate receptor, ionotropic, kainate 2

Identifiers

Type Value
pidENSP00000397026
HGNC4580
UniprotQ13002

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001662
IEA
Genome Projectbehavioral fear response
GO:0006810
NAS, IEA
Genome Projecttransport
GO:0006811
IEA
Genome Projection transport
GO:0006874
IEA
Genome Projectcellular calcium ion homeostasis
GO:0006886
IEA
Genome Projectintracellular protein transport
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007215
TAS
Genome Projectglutamate receptor signaling pathway
GO:0007268
TAS, IEA
Genome Projectsynaptic transmission
GO:0019228
IEA
Genome Projectneuronal action potential
GO:0034220
IBA
Genome Projection transmembrane transport
GO:0035235
IBA
Genome Projectionotropic glutamate receptor signaling pathway
GO:0035249
IBA
IEA
Genome Projectsynaptic transmission, glutamatergic
GO:0042391
IEA
Genome Projectregulation of membrane potential
GO:0043113
IEA
Genome Projectreceptor clustering
GO:0043524
IEA
Genome Projectnegative regulation of neuron apoptotic process
GO:0043525
IEA
Genome Projectpositive regulation of neuron apoptotic process
GO:0046328
IEA
Genome Projectregulation of JNK cascade
GO:0048169
IEA
Genome Projectregulation of long-term neuronal synaptic plasticity
GO:0048172
IMP
Genome Projectregulation of short-term neuronal synaptic plasticity
GO:0050804
IDA
Genome Projectmodulation of synaptic transmission
GO:0050806
IMP
Genome Projectpositive regulation of synaptic transmission
GO:0051402
IEA
Genome Projectneuron apoptotic process
GO:0051967
IEA
Genome Projectnegative regulation of synaptic transmission, glutamatergic
GO:0060079
IEA
Genome Projectexcitatory postsynaptic potential
GO:0060080
IEA
Genome Projectinhibitory postsynaptic potential

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004872
IEA
Genome Projectreceptor activity
GO:0004970
IEA
Genome Projectionotropic glutamate receptor activity
GO:0005216
IEA
Genome Projection channel activity
GO:0005234
IBA
IEA
Genome Projectextracellular-glutamate-gated ion channel activity
GO:0008066
IEA
Genome Projectglutamate receptor activity
GO:0015277
IDA
TAS, IEA
Genome Projectkainate selective glutamate receptor activity
GO:0030165
IEA
Genome ProjectPDZ domain binding
GO:0031624
IEA
Genome Projectubiquitin conjugating enzyme binding
GO:0031625
IEA
Genome Projectubiquitin protein ligase binding
GO:0042802
IEA
Genome Projectidentical protein binding
GO:0042803
IEA
Genome Projectprotein homodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
IBA
TAS, IEA
Genome Projectplasma membrane
GO:0005887
TAS, IEA
Genome Projectintegral component of plasma membrane
GO:0008328
IEA
Genome Projectionotropic glutamate receptor complex
GO:0014069
IEA
Genome Projectpostsynaptic density
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030054
IEA
Genome Projectcell junction
GO:0030424
IEA
Genome Projectaxon
GO:0030425
IBA
IEA
Genome Projectdendrite
GO:0032839
IEA
Genome Projectdendrite cytoplasm
GO:0032983
IBA
IEA
Genome Projectkainate selective glutamate receptor complex
GO:0042734
IBA
IEA
Genome Projectpresynaptic membrane
GO:0043025
IEA
Genome Projectneuronal cell body
GO:0043195
IEA
Genome Projectterminal bouton
GO:0043204
IEA
Genome Projectperikaryon
GO:0045202
IEA
Genome Projectsynapse
GO:0045211
IBA
IEA
Genome Projectpostsynaptic membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001320Ionotropic glutamate receptor
IPR001508Ionotropic glutamate receptor, metazoa
IPR001828Receptor, ligand binding region
IPR019594Ionotropic glutamate receptor, L-glutamate and glycine-binding domain
IPR028082Periplasmic binding protein-like I

No MapMan annotations defined for this gene.