Gene: ENSG00000164104 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000164104
Transcript Identifier
ENST00000446922
Gene Type
Coding gene
Location
4 : 173332080-173333649 : negative

Family Information

Homologous gene family
HOM03P000209
(166 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P066800
(2 genes in 2 species)
specific family

Descriptions

gene_descr
high mobility group box 2

Identifiers

Type Value
pidENSP00000393448
HGNC5000
UniprotP26583

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001938
IDA
Genome Projectpositive regulation of endothelial cell proliferation
GO:0002437
ISS
Genome Projectinflammatory response to antigenic stimulus
GO:0006265
ISS
Genome ProjectDNA topological change
GO:0006309
TAS
Genome Projectapoptotic DNA fragmentation
GO:0006325
NAS
Genome Projectchromatin organization
GO:0006334
NAS
Genome Projectnucleosome assembly
GO:0006338
IBA
Genome Projectchromatin remodeling
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IDA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0006915
TAS
Genome Projectapoptotic process
GO:0006921
TAS
Genome Projectcellular component disassembly involved in execution phase of apoptosis
GO:0007283
IEA
Genome Projectspermatogenesis
GO:0007289
IEA
Genome Projectspermatid nucleus differentiation
GO:0008584
IEA
Genome Projectmale gonad development
GO:0012501
TAS
Genome Projectprogrammed cell death
GO:0032075
IDA
Genome Projectpositive regulation of nuclease activity
GO:0032392
ISS
Genome ProjectDNA geometric change
GO:0032496
ISS
Genome Projectresponse to lipopolysaccharide
GO:0033151
ISS
Genome ProjectV(D)J recombination
GO:0042493
ISS
Genome Projectresponse to drug
GO:0043388
IDA
Genome Projectpositive regulation of DNA binding
GO:0045595
IEA
Genome Projectregulation of cell differentiation
GO:0045648
IMP
Genome Projectpositive regulation of erythrocyte differentiation
GO:0045654
IMP
Genome Projectpositive regulation of megakaryocyte differentiation
GO:0045892
IDA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
IDA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048545
IEA
Genome Projectresponse to steroid hormone
GO:0050767
ISS
Genome Projectregulation of neurogenesis
GO:0050829
IDA
Genome Projectdefense response to Gram-negative bacterium
GO:0050830
IDA
Genome Projectdefense response to Gram-positive bacterium
GO:0050918
IDA
Genome Projectpositive chemotaxis
GO:0051103
ISS
Genome ProjectDNA ligation involved in DNA repair
GO:0060326
IDA
Genome Projectcell chemotaxis
GO:0071222
IEP
Genome Projectcellular response to lipopolysaccharide
GO:0072091
ISS
Genome Projectregulation of stem cell proliferation
GO:1902042
IEA
Genome Projectnegative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000400
ISS
Genome Projectfour-way junction DNA binding
GO:0001158
ISS
Genome Projectenhancer sequence-specific DNA binding
GO:0003677
IMP
IEA
Genome ProjectDNA binding
GO:0003682
IBA
Genome Projectchromatin binding
GO:0003684
IDA
Genome Projectdamaged DNA binding
GO:0003690
ISS
Genome Projectdouble-stranded DNA binding
GO:0003697
ISS
Genome Projectsingle-stranded DNA binding
GO:0003700
IDA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
ISS
Genome Projecttranscription factor binding
GO:0008144
ISS
Genome Projectdrug binding
GO:0008301
IDA
Genome ProjectDNA binding, bending
GO:0019904
IEA
Genome Projectprotein domain specific binding
GO:0042056
IDA
Genome Projectchemoattractant activity
GO:0044212
IDA
Genome Projecttranscription regulatory region DNA binding
GO:0044378
ISS
Genome Projectnon-sequence-specific DNA binding, bending
GO:0044822
IDA
Genome Projectpoly(A) RNA binding
GO:0050786
IGI
Genome ProjectRAGE receptor binding
GO:0097100
ISS
Genome Projectsupercoiled DNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000790
ISS
Genome Projectnuclear chromatin
GO:0000793
IDA
Genome Projectcondensed chromosome
GO:0005615
IDA
Genome Projectextracellular space
GO:0005623
IDA
Genome Projectcell
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005694
IEA
Genome Projectchromosome
GO:0005737
IDA
Genome Projectcytoplasm
GO:0043234
IDA
Genome Projectprotein complex
GO:0048471
IDA
Genome Projectperinuclear region of cytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR009071High mobility group box domain
IPR017967HMG box A DNA-binding domain, conserved site
IPR031075High mobility group protein HMGB2

No MapMan annotations defined for this gene.