Gene: ENSG00000163739 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000163739
Transcript Identifier
ENST00000395761
Gene Type
Coding gene
Location
4 : 73869471-73870536 : positive

Family Information

Homologous gene family
HOM03P006025
(15 genes in 2 species)
specific family
Orthologous gene family
ORTHO03P032194
(3 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)

Identifiers

Type Value
pidENSP00000379110
HGNC4602
UniprotP09341

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002690
IBA
Genome Projectpositive regulation of leukocyte chemotaxis
GO:0006935
TAS
Genome Projectchemotaxis
GO:0006954
TAS, IEA
Genome Projectinflammatory response
GO:0006955
IBA
IEA
Genome Projectimmune response
GO:0007165
TAS
Genome Projectsignal transduction
GO:0007186
TAS
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007399
TAS
Genome Projectnervous system development
GO:0008283
TAS
Genome Projectcell proliferation
GO:0008285
TAS
Genome Projectnegative regulation of cell proliferation
GO:0030036
TAS
Genome Projectactin cytoskeleton organization
GO:0032496
IBA
Genome Projectresponse to lipopolysaccharide
GO:0035556
TAS
Genome Projectintracellular signal transduction
GO:0043085
TAS
Genome Projectpositive regulation of catalytic activity
GO:0060326
TAS, IEA
Genome Projectcell chemotaxis
GO:0070098
IBA
Genome Projectchemokine-mediated signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005102
TAS
Genome Projectreceptor binding
GO:0005125
IEA
Genome Projectcytokine activity
GO:0008009
TAS, IEA
Genome Projectchemokine activity
GO:0008047
TAS
Genome Projectenzyme activator activity
GO:0008083
IEA
Genome Projectgrowth factor activity
GO:0045236
IBA
Genome ProjectCXCR chemokine receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS, IEA
Genome Projectextracellular region
GO:0005615
TAS, IEA
Genome Projectextracellular space
GO:0005622
TAS
Genome Projectintracellular

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001089CXC chemokine
IPR001811Chemokine interleukin-8-like domain
IPR018048CXC chemokine, conserved site

No MapMan annotations defined for this gene.