Gene: ENSG00000163558 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000163558
Transcript Identifier
ENST00000295797
Gene Type
Coding gene
Location
3 : 170222670-170303127 : positive

Family Information

Homologous gene family
HOM03P000015
(1237 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P014902
(6 genes in 4 species)
specific family

Descriptions

gene_descr
protein kinase C, iota

Identifiers

Type Value
pidENSP00000295797
HGNC9404
UniprotP41743

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006468
IDA
IEA
Genome Projectprotein phosphorylation
GO:0006612
NAS
Genome Projectprotein targeting to membrane
GO:0007010
NAS
Genome Projectcytoskeleton organization
GO:0007015
IEA
Genome Projectactin filament organization
GO:0010976
IMP
Genome Projectpositive regulation of neuron projection development
GO:0016192
TAS
Genome Projectvesicle-mediated transport
GO:0016310
IEA
Genome Projectphosphorylation
GO:0016477
IEA
Genome Projectcell migration
GO:0032869
ISS
IEA
Genome Projectcellular response to insulin stimulus
GO:0034329
TAS
Genome Projectcell junction assembly
GO:0034351
IMP
Genome Projectnegative regulation of glial cell apoptotic process
GO:0034613
IEA
Genome Projectcellular protein localization
GO:0035089
IEA
Genome Projectestablishment of apical/basal cell polarity
GO:0035556
IEA
Genome Projectintracellular signal transduction
GO:0042462
IEA
Genome Projecteye photoreceptor cell development
GO:0043066
TAS
Genome Projectnegative regulation of apoptotic process
GO:0043434
IEA
Genome Projectresponse to peptide hormone
GO:0043524
IDA
Genome Projectnegative regulation of neuron apoptotic process
GO:0045197
TAS
Genome Projectestablishment or maintenance of epithelial cell apical/basal polarity
GO:0045216
IMP
TAS
Genome Projectcell-cell junction organization
GO:0046326
ISS
IEA
Genome Projectpositive regulation of glucose import
GO:0046903
NAS
Genome Projectsecretion
GO:0048011
TAS
Genome Projectneurotrophin TRK receptor signaling pathway
GO:0048194
IEA
Genome ProjectGolgi vesicle budding
GO:0051092
IDA
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0060252
IMP
Genome Projectpositive regulation of glial cell proliferation
GO:0061024
NAS
Genome Projectmembrane organization
GO:0070555
IEA
Genome Projectresponse to interleukin-1
GO:0070830
TAS
Genome Projectbicellular tight junction assembly
GO:0090004
ISS
IEA
Genome Projectpositive regulation of establishment of protein localization to plasma membrane
GO:2000353
IMP
Genome Projectpositive regulation of endothelial cell apoptotic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IDA
IEA
Genome Projectprotein kinase activity
GO:0004674
IDA
TAS, IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004697
ISS
IEA
Genome Projectprotein kinase C activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
TAS, IEA
Genome ProjectATP binding
GO:0005543
IDA
Genome Projectphospholipid binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0019904
IEA
Genome Projectprotein domain specific binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000139
IEA
Genome ProjectGolgi membrane
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005768
IEA
Genome Projectendosome
GO:0005829
IDA
TAS
Genome Projectcytosol
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005923
IEA
Genome Projectbicellular tight junction
GO:0015630
IDA
Genome Projectmicrotubule cytoskeleton
GO:0016020
IEA
Genome Projectmembrane
GO:0016324
IEA
Genome Projectapical plasma membrane
GO:0031252
IEA
Genome Projectcell leading edge
GO:0043220
IEA
Genome ProjectSchmidt-Lanterman incisure
GO:0043234
IEA
Genome Projectprotein complex
GO:0045171
IDA
Genome Projectintercellular bridge
GO:0045177
IEA
Genome Projectapical part of cell
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000270PB1 domain
IPR000719Protein kinase domain
IPR000961AGC-kinase, C-terminal
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR012233Protein kinase C
IPR017441Protein kinase, ATP binding site
IPR020454Diacylglycerol/phorbol-ester binding

No MapMan annotations defined for this gene.