Gene: ENSG00000163485 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000163485
Transcript Identifier
ENST00000337894
Gene Type
Coding gene
Location
1 : 203128842-203165900 : positive

Family Information

Homologous gene family
HOM03P000241
(150 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P067374
(2 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
adenosine A1 receptor

Identifiers

Type Value
pidENSP00000338435
HGNC262
UniprotP30542

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000186
IEA
Genome Projectactivation of MAPKK activity
GO:0001659
IEA
Genome Projecttemperature homeostasis
GO:0001666
IEA
Genome Projectresponse to hypoxia
GO:0001973
IEA
Genome Projectadenosine receptor signaling pathway
GO:0002087
IEA
Genome Projectregulation of respiratory gaseous exchange by neurological system process
GO:0002674
IEA
Genome Projectnegative regulation of acute inflammatory response
GO:0002686
IEA
Genome Projectnegative regulation of leukocyte migration
GO:0002793
IEA
Genome Projectpositive regulation of peptide secretion
GO:0003093
IEA
Genome Projectregulation of glomerular filtration
GO:0006612
IEA
Genome Projectprotein targeting to membrane
GO:0006909
TAS
Genome Projectphagocytosis
GO:0006954
TAS
Genome Projectinflammatory response
GO:0007165
TAS, IEA
Genome Projectsignal transduction
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007193
IEA
Genome Projectadenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007267
TAS
Genome Projectcell-cell signaling
GO:0007399
TAS
Genome Projectnervous system development
GO:0008285
IEA
Genome Projectnegative regulation of cell proliferation
GO:0014050
IEA
Genome Projectnegative regulation of glutamate secretion
GO:0016042
IEA
Genome Projectlipid catabolic process
GO:0032229
IEA
Genome Projectnegative regulation of synaptic transmission, GABAergic
GO:0032244
IEA
Genome Projectpositive regulation of nucleoside transport
GO:0032900
IEA
Genome Projectnegative regulation of neurotrophin production
GO:0035307
IEA
Genome Projectpositive regulation of protein dephosphorylation
GO:0035814
IEA
Genome Projectnegative regulation of renal sodium excretion
GO:0042321
IEA
Genome Projectnegative regulation of circadian sleep/wake cycle, sleep
GO:0042323
IEA
Genome Projectnegative regulation of circadian sleep/wake cycle, non-REM sleep
GO:0043066
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043268
IEA
Genome Projectpositive regulation of potassium ion transport
GO:0045741
IEA
Genome Projectpositive regulation of epidermal growth factor-activated receptor activity
GO:0045776
IEA
Genome Projectnegative regulation of blood pressure
GO:0045777
IEA
Genome Projectpositive regulation of blood pressure
GO:0045822
IEA
Genome Projectnegative regulation of heart contraction
GO:0045908
IEA
Genome Projectnegative regulation of vasodilation
GO:0046888
IEA
Genome Projectnegative regulation of hormone secretion
GO:0048167
IEA
Genome Projectregulation of synaptic plasticity
GO:0050728
IEA
Genome Projectnegative regulation of inflammatory response
GO:0050890
IEA
Genome Projectcognition
GO:0050965
IEA
Genome Projectdetection of temperature stimulus involved in sensory perception of pain
GO:0050995
IEA
Genome Projectnegative regulation of lipid catabolic process
GO:0051930
IEA
Genome Projectregulation of sensory perception of pain
GO:0051967
IEA
Genome Projectnegative regulation of synaptic transmission, glutamatergic
GO:0055117
IEA
Genome Projectregulation of cardiac muscle contraction
GO:0055118
IEA
Genome Projectnegative regulation of cardiac muscle contraction
GO:0060079
IEA
Genome Projectexcitatory postsynaptic potential
GO:0060087
IEA
Genome Projectrelaxation of vascular smooth muscle
GO:0070256
IEA
Genome Projectnegative regulation of mucus secretion
GO:0097190
TAS
Genome Projectapoptotic signaling pathway
GO:1900453
IEA
Genome Projectnegative regulation of long term synaptic depression

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001609
IEA
Genome ProjectG-protein coupled adenosine receptor activity
GO:0001664
IEA
Genome ProjectG-protein coupled receptor binding
GO:0001883
IEA
Genome Projectpurine nucleoside binding
GO:0004629
IEA
Genome Projectphospholipase C activity
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0031683
IEA
Genome ProjectG-protein beta/gamma-subunit complex binding
GO:0032795
IEA
Genome Projectheterotrimeric G-protein binding
GO:0046982
IEA
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005783
IEA
Genome Projectendoplasmic reticulum
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005887
TAS
Genome Projectintegral component of plasma membrane
GO:0012505
IEA
Genome Projectendomembrane system
GO:0014069
IEA
Genome Projectpostsynaptic density
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0016323
IEA
Genome Projectbasolateral plasma membrane
GO:0030425
IEA
Genome Projectdendrite
GO:0030673
IEA
Genome Projectaxolemma
GO:0032279
IEA
Genome Projectasymmetric synapse
GO:0042734
IEA
Genome Projectpresynaptic membrane
GO:0043025
IEA
Genome Projectneuronal cell body
GO:0043195
IEA
Genome Projectterminal bouton
GO:0043197
IEA
Genome Projectdendritic spine
GO:0044297
IEA
Genome Projectcell body
GO:0045202
IEA
Genome Projectsynapse
GO:0045211
IEA
Genome Projectpostsynaptic membrane
GO:0048786
IEA
Genome Projectpresynaptic active zone

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000276G protein-coupled receptor, rhodopsin-like
IPR001068Adenosine A1 receptor
IPR001634Adenosine receptor
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.