Gene: ENSG00000163132 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000163132
Transcript Identifier
ENST00000382723
Gene Type
Coding gene
Location
4 : 4859900-4863143 : positive

Family Information

Homologous gene family
HOM03P000104
(258 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P076265
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
msh homeobox 1

Identifiers

Type Value
pidENSP00000372170
HGNC7391
UniprotP28360

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0000902
IDA
Genome Projectcell morphogenesis
GO:0001701
IEA
Genome Projectin utero embryonic development
GO:0001837
IEA
Genome Projectepithelial to mesenchymal transition
GO:0003007
IEA
Genome Projectheart morphogenesis
GO:0003198
IEA
Genome Projectepithelial to mesenchymal transition involved in endocardial cushion formation
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006366
IEA
Genome Projecttranscription from RNA polymerase II promoter
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007507
IEA
Genome Projectheart development
GO:0007517
IEA
Genome Projectmuscle organ development
GO:0008285
IEA
Genome Projectnegative regulation of cell proliferation
GO:0009952
IEA
Genome Projectanterior/posterior pattern specification
GO:0010463
IEA
Genome Projectmesenchymal cell proliferation
GO:0023019
IEA
Genome Projectsignal transduction involved in regulation of gene expression
GO:0030308
IDA
Genome Projectnegative regulation of cell growth
GO:0030326
IEA
Genome Projectembryonic limb morphogenesis
GO:0030509
IEA
Genome ProjectBMP signaling pathway
GO:0030513
IEA
Genome Projectpositive regulation of BMP signaling pathway
GO:0030900
IEA
Genome Projectforebrain development
GO:0030901
IEA
Genome Projectmidbrain development
GO:0034504
IDA
Genome Projectprotein localization to nucleus
GO:0035115
IEA
Genome Projectembryonic forelimb morphogenesis
GO:0035116
IEA
Genome Projectembryonic hindlimb morphogenesis
GO:0035880
IMP
Genome Projectembryonic nail plate morphogenesis
GO:0042474
IEA
Genome Projectmiddle ear morphogenesis
GO:0042475
IMP
Genome Projectodontogenesis of dentin-containing tooth
GO:0042476
IEA
Genome Projectodontogenesis
GO:0042481
IEA
Genome Projectregulation of odontogenesis
GO:0042733
IEA
Genome Projectembryonic digit morphogenesis
GO:0043066
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043392
IEA
Genome Projectnegative regulation of DNA binding
GO:0043517
IC
Genome Projectpositive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0045892
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045944
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048863
IEA
Genome Projectstem cell differentiation
GO:0050821
IDA
Genome Projectprotein stabilization
GO:0051154
IEA
Genome Projectnegative regulation of striated muscle cell differentiation
GO:0060021
IEA
Genome Projectpalate development
GO:0060325
IMP
Genome Projectface morphogenesis
GO:0060349
IEA
Genome Projectbone morphogenesis
GO:0060536
IEA
Genome Projectcartilage morphogenesis
GO:0061180
IEA
Genome Projectmammary gland epithelium development
GO:0061312
IEA
Genome ProjectBMP signaling pathway involved in heart development
GO:0090427
IEA
Genome Projectactivation of meiosis
GO:1902255
IDA
Genome Projectpositive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
GO:2000678
IEA
Genome Projectnegative regulation of transcription regulatory region DNA binding
GO:2001055
IEA
Genome Projectpositive regulation of mesenchymal cell apoptotic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000977
IEA
Genome ProjectRNA polymerase II regulatory region sequence-specific DNA binding
GO:0000982
IEA
Genome Projecttranscription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001227
IEA
Genome Projecttranscriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0001228
IEA
Genome Projecttranscriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0002039
IPI
Genome Projectp53 binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005737
IDA
Genome Projectcytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001356Homeobox domain
IPR009057Homeodomain-like
IPR017970Homeobox, conserved site
IPR020479Homeodomain, metazoa

No MapMan annotations defined for this gene.