Gene: ENSG00000162999 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000162999
Transcript Identifier
ENST00000354221
Gene Type
Coding gene
Location
2 : 183078934-183095658 : positive

Family Information

Homologous gene family
HOM03P000093
(285 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P008120
(10 genes in 2 species)
specific family

Descriptions

gene_descr
dual specificity phosphatase 19

Identifiers

Type Value
pidENSP00000346160
HGNC18894
UniprotQ8WTR2

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000188
IEA
Genome Projectinactivation of MAPK activity
GO:0006469
ISS
Genome Projectnegative regulation of protein kinase activity
GO:0006470
IBA
IEA
Genome Projectprotein dephosphorylation
GO:0007254
IBA
IEA
Genome ProjectJNK cascade
GO:0016311
IEA
Genome Projectdephosphorylation
GO:0032147
ISS
Genome Projectactivation of protein kinase activity
GO:0035335
IEA
Genome Projectpeptidyl-tyrosine dephosphorylation
GO:0043410
ISS
Genome Projectpositive regulation of MAPK cascade
GO:0043507
ISS
Genome Projectpositive regulation of JUN kinase activity
GO:0043508
ISS
Genome Projectnegative regulation of JUN kinase activity
GO:0045860
ISS
Genome Projectpositive regulation of protein kinase activity
GO:0046329
ISS
Genome Projectnegative regulation of JNK cascade
GO:0046330
ISS
Genome Projectpositive regulation of JNK cascade
GO:1904030
ISS
Genome Projectnegative regulation of cyclin-dependent protein kinase activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004721
IEA
Genome Projectphosphoprotein phosphatase activity
GO:0004725
IEA
Genome Projectprotein tyrosine phosphatase activity
GO:0004860
ISS
Genome Projectprotein kinase inhibitor activity
GO:0005078
ISS
Genome ProjectMAP-kinase scaffold activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008138
IEA
Genome Projectprotein tyrosine/serine/threonine phosphatase activity
GO:0008330
IEA
Genome Projectprotein tyrosine/threonine phosphatase activity
GO:0008579
IBA
IEA
Genome ProjectJUN kinase phosphatase activity
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0016791
IEA
Genome Projectphosphatase activity
GO:0030295
ISS
Genome Projectprotein kinase activator activity
GO:0031435
ISS
Genome Projectmitogen-activated protein kinase kinase kinase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000340Dual specificity phosphatase, catalytic domain
IPR000387Tyrosine specific protein phosphatases domain
IPR020417Atypical dual specificity phosphatase
IPR020422Dual specificity protein phosphatase domain
IPR024950Dual specificity phosphatase
IPR029021Protein-tyrosine phosphatase-like

No MapMan annotations defined for this gene.