Gene: ENSG00000162924 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000162924
Transcript Identifier
ENST00000295025
Gene Type
Coding gene
Location
2 : 60881841-60922535 : positive

Family Information

Homologous gene family
HOM03P008110
(10 genes in 3 species)
specific family
Orthologous gene family
ORTHO03P025181
(4 genes in 3 species)
specific family

Descriptions

gene_descr
v-rel avian reticuloendotheliosis viral oncogene homolog

Identifiers

Type Value
pidENSP00000295025
HGNC9954
UniprotQ04864

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IBA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001816
IEA
Genome Projectcytokine production
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006366
IDA
Genome Projecttranscription from RNA polymerase II promoter
GO:0006954
IBA
Genome Projectinflammatory response
GO:0007249
IBA
IEA
Genome ProjectI-kappaB kinase/NF-kappaB signaling
GO:0010629
IDA
Genome Projectnegative regulation of gene expression
GO:0032688
IDA
Genome Projectnegative regulation of interferon-beta production
GO:0034097
IBA
Genome Projectresponse to cytokine
GO:0038061
IBA
Genome ProjectNIK/NF-kappaB signaling
GO:0043123
IEP
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045084
IEA
Genome Projectpositive regulation of interleukin-12 biosynthetic process
GO:0045087
IBA
Genome Projectinnate immune response
GO:0045893
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:1901215
IEA
Genome Projectnegative regulation of neuron death

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000980
IDA
Genome ProjectRNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001205
IDA
Genome Projecttranscriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003682
IBA
Genome Projectchromatin binding
GO:0003700
NAS, IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IMP
IEA
Genome Projectnucleus
GO:0005654
IBA
TAS
Genome Projectnucleoplasm
GO:0005667
IEA
Genome Projecttranscription factor complex
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005829
IBA
TAS
Genome Projectcytosol
GO:0033256
IBA
Genome ProjectI-kappaB/NF-kappaB complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000451NF-kappa-B/Dorsal
IPR002909IPT domain
IPR008967p53-like transcription factor, DNA-binding
IPR011539Rel homology domain (RHD), DNA-binding domain
IPR013783Immunoglobulin-like fold
IPR014756Immunoglobulin E-set
IPR030492Rel homology domain, conserved site
IPR030505Proto-oncogene c-Rel
IPR032397Rel homology dimerisation domain

No MapMan annotations defined for this gene.