Gene: ENSG00000162552 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000162552
Transcript Identifier
ENST00000290167
Gene Type
Coding gene
Location
1 : 22120050-22142922 : negative

Family Information

Homologous gene family
HOM03P001537
(49 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P041982
(3 genes in 3 species)
specific family

Descriptions

gene_descr
wingless-type MMTV integration site family, member 4

Identifiers

Type Value
pidENSP00000290167
HGNC12783
UniprotP56705

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001656
IEA
Genome Projectmetanephros development
GO:0001658
IEA
Genome Projectbranching involved in ureteric bud morphogenesis
GO:0001822
IEP
Genome Projectkidney development
GO:0001823
IEA
Genome Projectmesonephros development
GO:0001837
IEP
Genome Projectepithelial to mesenchymal transition
GO:0001838
IEA
Genome Projectembryonic epithelial tube formation
GO:0001889
IEP
Genome Projectliver development
GO:0006702
IDA
Genome Projectandrogen biosynthetic process
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007276
IEA
Genome Projectgamete generation
GO:0007548
IEA
Genome Projectsex differentiation
GO:0008584
IMP, IEP
Genome Projectmale gonad development
GO:0008585
ISS
IEA
Genome Projectfemale gonad development
GO:0009267
IEA
Genome Projectcellular response to starvation
GO:0010629
IDA
Genome Projectnegative regulation of gene expression
GO:0010894
IDA
Genome Projectnegative regulation of steroid biosynthetic process
GO:0016055
IEA
Genome ProjectWnt signaling pathway
GO:0022407
IEA
Genome Projectregulation of cell-cell adhesion
GO:0030154
IEA
Genome Projectcell differentiation
GO:0030182
IBA
Genome Projectneuron differentiation
GO:0030237
IMP
Genome Projectfemale sex determination
GO:0030325
IEP
Genome Projectadrenal gland development
GO:0030336
IEA
Genome Projectnegative regulation of cell migration
GO:0030501
IDA
Genome Projectpositive regulation of bone mineralization
GO:0032349
IDA
Genome Projectpositive regulation of aldosterone biosynthetic process
GO:0032967
IDA
Genome Projectpositive regulation of collagen biosynthetic process
GO:0033077
IEA
Genome ProjectT cell differentiation in thymus
GO:0033080
IEA
Genome Projectimmature T cell proliferation in thymus
GO:0035239
IEA
Genome Projecttube morphogenesis
GO:0035567
IEA
Genome Projectnon-canonical Wnt signaling pathway
GO:0038030
IDA
Genome Projectnon-canonical Wnt signaling pathway via MAPK cascade
GO:0040037
IEA
Genome Projectnegative regulation of fibroblast growth factor receptor signaling pathway
GO:0042445
IEA
Genome Projecthormone metabolic process
GO:0043547
IEA
Genome Projectpositive regulation of GTPase activity
GO:0045165
IBA
IEA
Genome Projectcell fate commitment
GO:0045596
IEA
Genome Projectnegative regulation of cell differentiation
GO:0045669
IDA
Genome Projectpositive regulation of osteoblast differentiation
GO:0045836
IEA
Genome Projectpositive regulation of meiotic nuclear division
GO:0045892
IMP
ISS
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
IDA
ISS
Genome Projectpositive regulation of transcription, DNA-templated
GO:0048599
IEA
Genome Projectoocyte development
GO:0048754
IEA
Genome Projectbranching morphogenesis of an epithelial tube
GO:0048856
IEA
Genome Projectanatomical structure development
GO:0051145
IEA
Genome Projectsmooth muscle cell differentiation
GO:0051496
IEA
Genome Projectpositive regulation of stress fiber assembly
GO:0051894
IEA
Genome Projectpositive regulation of focal adhesion assembly
GO:0060070
IDA
Genome Projectcanonical Wnt signaling pathway
GO:0060126
IEA
Genome Projectsomatotropin secreting cell differentiation
GO:0060129
IEA
Genome Projectthyroid-stimulating hormone-secreting cell differentiation
GO:0060231
IEA
Genome Projectmesenchymal to epithelial transition
GO:0060748
IEA
Genome Projecttertiary branching involved in mammary gland duct morphogenesis
GO:0060993
IEA
Genome Projectkidney morphogenesis
GO:0061045
IEA
Genome Projectnegative regulation of wound healing
GO:0061180
IEP
Genome Projectmammary gland epithelium development
GO:0061184
IDA
Genome Projectpositive regulation of dermatome development
GO:0061205
IMP
Genome Projectparamesonephric duct development
GO:0061369
IMP
Genome Projectnegative regulation of testicular blood vessel morphogenesis
GO:0071560
IEP
Genome Projectcellular response to transforming growth factor beta stimulus
GO:0072006
IEA
Genome Projectnephron development
GO:0072033
IEA
Genome Projectrenal vesicle formation
GO:0072034
IEA
Genome Projectrenal vesicle induction
GO:0072162
NAS
Genome Projectmetanephric mesenchymal cell differentiation
GO:0072164
IEA
Genome Projectmesonephric tubule development
GO:0072174
IEA
Genome Projectmetanephric tubule formation
GO:0072210
IEA
Genome Projectmetanephric nephron development
GO:0072273
IEA
Genome Projectmetanephric nephron morphogenesis
GO:0090002
IDA
Genome Projectestablishment of protein localization to plasma membrane
GO:0090090
IDA
TAS
Genome Projectnegative regulation of canonical Wnt signaling pathway
GO:0090263
IDA
Genome Projectpositive regulation of canonical Wnt signaling pathway
GO:2000019
IMP
Genome Projectnegative regulation of male gonad development
GO:2000066
IDA
Genome Projectpositive regulation of cortisol biosynthetic process
GO:2000225
IMP
Genome Projectnegative regulation of testosterone biosynthetic process
GO:2001234
IEA
Genome Projectnegative regulation of apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003714
ISS
IEA
Genome Projecttranscription corepressor activity
GO:0005102
IEA
Genome Projectreceptor binding
GO:0005109
IBA
IEA
Genome Projectfrizzled binding
GO:0048018
IC
Genome Projectreceptor agonist activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS, IEA
Genome Projectextracellular region
GO:0005578
IEA
Genome Projectproteinaceous extracellular matrix
GO:0005615
IDA
Genome Projectextracellular space
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005788
TAS
Genome Projectendoplasmic reticulum lumen
GO:0005796
TAS
Genome ProjectGolgi lumen
GO:0005886
TAS
Genome Projectplasma membrane
GO:0009986
ISS
IEA
Genome Projectcell surface

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR005817Wnt
IPR009142Wnt-4 protein
IPR018161Wnt protein, conserved site

No MapMan annotations defined for this gene.