Gene: ENSG00000160973 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000160973
Transcript Identifier
ENST00000377317
Gene Type
Coding gene
Location
8 : 144474238-144475756 : negative

Family Information

Homologous gene family
HOM03P000483
(99 genes in 6 species)
specific family
Orthologous gene family
ORTHO03P072068
(2 genes in 2 species)
specific family

Descriptions

gene_descr
forkhead box H1

Identifiers

Type Value
pidENSP00000366534
HGNC3814
UniprotO75593

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001947
IEA
Genome Projectheart looping
GO:0003139
IEA
Genome Projectsecondary heart field specification
GO:0003151
IEA
Genome Projectoutflow tract morphogenesis
GO:0003215
IEA
Genome Projectcardiac right ventricle morphogenesis
GO:0003222
IEA
Genome Projectventricular trabecula myocardium morphogenesis
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IEA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0006366
IEA
Genome Projecttranscription from RNA polymerase II promoter
GO:0007179
ISS
TAS, IEA
Genome Projecttransforming growth factor beta receptor signaling pathway
GO:0007368
IEA
Genome Projectdetermination of left/right symmetry
GO:0009653
IBA
Genome Projectanatomical structure morphogenesis
GO:0009952
IEA
Genome Projectanterior/posterior pattern specification
GO:0030154
IBA
Genome Projectcell differentiation
GO:0033147
IDA
Genome Projectnegative regulation of intracellular estrogen receptor signaling pathway
GO:0035054
IEA
Genome Projectembryonic heart tube anterior/posterior pattern specification
GO:0035909
IEA
Genome Projectaorta morphogenesis
GO:0045893
IDA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048318
IEA
Genome Projectaxial mesoderm development
GO:0060766
IDA
Genome Projectnegative regulation of androgen receptor signaling pathway
GO:1900164
NAS
Genome Projectnodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
GO:2000824
IDA
Genome Projectnegative regulation of androgen receptor activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000981
IBA
Genome ProjectRNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0001104
IEA
Genome ProjectRNA polymerase II transcription cofactor activity
GO:0001190
IEA
Genome Projecttranscriptional activator activity, RNA polymerase II transcription factor binding
GO:0001205
IEA
Genome Projecttranscriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0003677
IDA
IEA
Genome ProjectDNA binding
GO:0003700
IDA
NAS, IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0019904
IPI
Genome Projectprotein domain specific binding
GO:0035326
IC
Genome Projectenhancer binding
GO:0043425
IPI
Genome ProjectbHLH transcription factor binding
GO:0043565
IDA
IEA
Genome Projectsequence-specific DNA binding
GO:0044212
ISS
IEA
Genome Projecttranscription regulatory region DNA binding
GO:0046332
IPI
Genome ProjectSMAD binding
GO:0050681
IPI
Genome Projectandrogen receptor binding
GO:0070410
IMP
Genome Projectco-SMAD binding
GO:0070412
IPI, IMP
Genome ProjectR-SMAD binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000790
IDA
Genome Projectnuclear chromatin
GO:0005634
IDA
IC, IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005667
IDA
Genome Projecttranscription factor complex
GO:0032444
IDA
Genome Projectactivin responsive factor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001766Fork head domain
IPR011991Winged helix-turn-helix DNA-binding domain

No MapMan annotations defined for this gene.