Gene: ENSG00000160716 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000160716
Transcript Identifier
ENST00000368476
Gene Type
Coding gene
Location
1 : 154568045-154575932 : positive

Family Information

Homologous gene family
HOM03P000517
(94 genes in 7 species)
specific family
Orthologous gene family
ORTHO03P024703
(4 genes in 2 species)
specific family

Descriptions

gene_descr
cholinergic receptor, nicotinic, beta 2 (neuronal)

Identifiers

Type Value
pidENSP00000357461
HGNC1962
UniprotP17787
UniprotQ5SXY3

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001508
IEA
Genome Projectaction potential
GO:0001661
IEA
Genome Projectconditioned taste aversion
GO:0001666
IDA
Genome Projectresponse to hypoxia
GO:0006810
IEA
Genome Projecttransport
GO:0006811
NAS, IEA
Genome Projection transport
GO:0006816
ISS
IEA
Genome Projectcalcium ion transport
GO:0006939
ISS
IEA
Genome Projectsmooth muscle contraction
GO:0007165
IDA
Genome Projectsignal transduction
GO:0007268
TAS
Genome Projectsynaptic transmission
GO:0007271
ISS, IBA
IEA
Genome Projectsynaptic transmission, cholinergic
GO:0007274
IBA
Genome Projectneuromuscular synaptic transmission
GO:0007601
ISS
IEA
Genome Projectvisual perception
GO:0007605
ISS
IEA
Genome Projectsensory perception of sound
GO:0007612
IMP
Genome Projectlearning
GO:0007613
IMP
Genome Projectmemory
GO:0007626
ISS
IEA
Genome Projectlocomotory behavior
GO:0008306
ISS
IEA
Genome Projectassociative learning
GO:0008542
IMP
Genome Projectvisual learning
GO:0014059
ISS
IEA
Genome Projectregulation of dopamine secretion
GO:0019233
ISS
IEA
Genome Projectsensory perception of pain
GO:0021562
ISS
IEA
Genome Projectvestibulocochlear nerve development
GO:0021631
ISS
IEA
Genome Projectoptic nerve morphogenesis
GO:0021771
ISS
IEA
Genome Projectlateral geniculate nucleus development
GO:0021952
ISS
IEA
Genome Projectcentral nervous system projection neuron axonogenesis
GO:0021955
IEA
Genome Projectcentral nervous system neuron axonogenesis
GO:0030890
ISS
Genome Projectpositive regulation of B cell proliferation
GO:0032225
ISS
IEA
Genome Projectregulation of synaptic transmission, dopaminergic
GO:0032226
IEA
Genome Projectpositive regulation of synaptic transmission, dopaminergic
GO:0033603
ISS
IEA
Genome Projectpositive regulation of dopamine secretion
GO:0034220
TAS, IEA
Genome Projection transmembrane transport
GO:0035094
IDA
IEA
Genome Projectresponse to nicotine
GO:0035095
IMP
Genome Projectbehavioral response to nicotine
GO:0035176
ISS
IEA
Genome Projectsocial behavior
GO:0042053
ISS
IEA
Genome Projectregulation of dopamine metabolic process
GO:0042113
ISS
IEA
Genome ProjectB cell activation
GO:0042220
ISS
IEA
Genome Projectresponse to cocaine
GO:0042320
ISS
IEA
Genome Projectregulation of circadian sleep/wake cycle, REM sleep
GO:0042391
IBA
IEA
Genome Projectregulation of membrane potential
GO:0045188
IEA
Genome Projectregulation of circadian sleep/wake cycle, non-REM sleep
GO:0045471
ISS
IEA
Genome Projectresponse to ethanol
GO:0045759
ISS
IEA
Genome Projectnegative regulation of action potential
GO:0048814
ISS
IEA
Genome Projectregulation of dendrite morphogenesis
GO:0050877
IMP
Genome Projectneurological system process
GO:0050890
IMP
Genome Projectcognition
GO:0051291
IEA
Genome Projectprotein heterooligomerization
GO:0051899
ISS
IEA
Genome Projectmembrane depolarization
GO:0051963
ISS
IEA
Genome Projectregulation of synapse assembly
GO:0060084
ISS
IEA
Genome Projectsynaptic transmission involved in micturition
GO:0098655
IDA
TAS, IEA
Genome Projectcation transmembrane transport

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004889
IDA
TAS, IEA
Genome Projectacetylcholine-activated cation-selective channel activity
GO:0005216
IEA
Genome Projection channel activity
GO:0005230
IEA
Genome Projectextracellular ligand-gated ion channel activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008144
IEA
Genome Projectdrug binding
GO:0015276
TAS
Genome Projectligand-gated ion channel activity
GO:0015464
IDA
Genome Projectacetylcholine receptor activity
GO:0042166
IMP
IC, IEA
Genome Projectacetylcholine binding
GO:0046982
IEA
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005892
IDA
IEA
Genome Projectacetylcholine-gated channel complex
GO:0009897
ISS
IEA
Genome Projectexternal side of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
NAS, IEA
Genome Projectintegral component of membrane
GO:0030054
IEA
Genome Projectcell junction
GO:0043005
IBA
Genome Projectneuron projection
GO:0045202
IBA
IEA
Genome Projectsynapse
GO:0045211
IEA
Genome Projectpostsynaptic membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002394Nicotinic acetylcholine receptor
IPR006029Neurotransmitter-gated ion-channel transmembrane domain
IPR006201Neurotransmitter-gated ion-channel
IPR006202Neurotransmitter-gated ion-channel ligand-binding domain
IPR018000Neurotransmitter-gated ion-channel, conserved site
IPR027361Nicotinic acetylcholine-gated receptor, transmembrane domain

No MapMan annotations defined for this gene.