Gene: ENSG00000160710 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000160710
Transcript Identifier
ENST00000368474
Gene Type
Coding gene
Location
1 : 154584806-154608006 : negative

Family Information

Homologous gene family
HOM03P002851
(33 genes in 27 species)
specific family

Descriptions

gene_descr
adenosine deaminase, RNA-specific

Identifiers

Type Value
pidENSP00000357459
HGNC225
UniprotP55265

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001649
IEA
Genome Projectosteoblast differentiation
GO:0001701
IEA
Genome Projectin utero embryonic development
GO:0002244
IEA
Genome Projecthematopoietic progenitor cell differentiation
GO:0002376
IEA
Genome Projectimmune system process
GO:0002566
IEA
Genome Projectsomatic diversification of immune receptors via somatic mutation
GO:0006382
IDA, IMP
TAS
Genome Projectadenosine to inosine editing
GO:0006396
IEA
Genome ProjectRNA processing
GO:0006397
IEA
Genome ProjectmRNA processing
GO:0006606
IDA
Genome Projectprotein import into nucleus
GO:0006611
IDA
Genome Projectprotein export from nucleus
GO:0009615
IMP
Genome Projectresponse to virus
GO:0010467
TAS
Genome Projectgene expression
GO:0016553
IDA
Genome Projectbase conversion or substitution editing
GO:0016556
TAS
Genome ProjectmRNA modification
GO:0019221
TAS
Genome Projectcytokine-mediated signaling pathway
GO:0030218
IEA
Genome Projecterythrocyte differentiation
GO:0031047
IEA
Genome Projectgene silencing by RNA
GO:0031054
IDA
Genome Projectpre-miRNA processing
GO:0035196
IEA
Genome Projectproduction of miRNAs involved in gene silencing by miRNA
GO:0035280
IDA
Genome ProjectmiRNA loading onto RISC involved in gene silencing by miRNA
GO:0035455
IDA
Genome Projectresponse to interferon-alpha
GO:0043066
IEA
Genome Projectnegative regulation of apoptotic process
GO:0044387
IDA, IMP
Genome Projectnegative regulation of protein kinase activity by regulation of protein phosphorylation
GO:0045070
IDA, IMP
Genome Projectpositive regulation of viral genome replication
GO:0045071
IEA
Genome Projectnegative regulation of viral genome replication
GO:0045087
TAS, IEA
Genome Projectinnate immune response
GO:0051607
IEA
Genome Projectdefense response to virus
GO:0060216
IEA
Genome Projectdefinitive hemopoiesis
GO:0060337
TAS
Genome Projecttype I interferon signaling pathway
GO:0060339
IEA
Genome Projectnegative regulation of type I interferon-mediated signaling pathway
GO:0061484
IEA
Genome Projecthematopoietic stem cell homeostasis
GO:1900369
IEA
Genome Projectnegative regulation of RNA interference

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003723
IEA
Genome ProjectRNA binding
GO:0003726
IDA
TAS, NAS, IEA
Genome Projectdouble-stranded RNA adenosine deaminase activity
GO:0004000
IEA
Genome Projectadenosine deaminase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0044822
IDA
Genome Projectpoly(A) RNA binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
TAS, IEA
Genome Projectnucleus
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005730
IDA
IEA
Genome Projectnucleolus
GO:0005737
IDA
TAS, IEA
Genome Projectcytoplasm
GO:0016020
IDA
Genome Projectmembrane
GO:0044530
IDA
Genome Projectsupraspliceosomal complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000607Double-stranded RNA-specific adenosine deaminase (DRADA)
IPR002466Adenosine deaminase/editase
IPR011991Winged helix-turn-helix DNA-binding domain
IPR014720Double-stranded RNA-binding domain

No MapMan annotations defined for this gene.