Gene: ENSG00000159593 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000159593
Transcript Identifier
ENST00000359087
Gene Type
Coding gene
Location
16 : 66803009-66830899 : negative

Family Information

Homologous gene family
HOM03P001631
(47 genes in 37 species)
specific family

Descriptions

gene_descr
NEDD8 activating enzyme E1 subunit 1

Identifiers

Type Value
pidENSP00000351990
HGNC621
UniprotQ13564

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006915
IEA
Genome Projectapoptotic process
GO:0007049
IEA
Genome Projectcell cycle
GO:0007165
TAS
Genome Projectsignal transduction
GO:0033314
IDA
Genome Projectmitotic DNA replication checkpoint
GO:0042981
IDA, IMP
Genome Projectregulation of apoptotic process
GO:0043523
IDA
Genome Projectregulation of neuron apoptotic process
GO:0045116
IDA
IEA
Genome Projectprotein neddylation
GO:0051402
IDA
Genome Projectneuron apoptotic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0008641
IEA
Genome Projectsmall protein activating enzyme activity
GO:0019781
IDA
IEA
Genome ProjectNEDD8 activating enzyme activity
GO:0031625
IPI
Genome Projectubiquitin protein ligase binding
GO:0046982
IPI
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IBA
Genome Projectnucleus
GO:0005737
TAS
Genome Projectcytoplasm
GO:0005829
IBA
Genome Projectcytosol
GO:0005886
IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000594THIF-type NAD/FAD binding fold
IPR030667NEDD8-activating enzyme E1 regulatory subunit APP-BP1

No MapMan annotations defined for this gene.