Gene: ENSG00000159131 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000159131
Transcript Identifier
ENST00000381839
Gene Type
Coding gene
Location
21 : 33504124-33539315 : negative

Family Information

Homologous gene family
HOM03P000993
(62 genes in 38 species)
specific family
Orthologous gene family
ORTHO03P001546
(37 genes in 35 species)
specific family

Descriptions

gene_descr
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase

Identifiers

Type Value
pidENSP00000371261
HGNC4163
UniprotP22102

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003360
IEA
Genome Projectbrainstem development
GO:0006144
TAS
Genome Projectpurine nucleobase metabolic process
GO:0006164
IEA
Genome Projectpurine nucleotide biosynthetic process
GO:0006189
IEA
Genome Project'de novo' IMP biosynthetic process
GO:0006544
IEA
Genome Projectglycine metabolic process
GO:0008152
IEA
Genome Projectmetabolic process
GO:0009058
IEA
Genome Projectbiosynthetic process
GO:0009113
IEA
Genome Projectpurine nucleobase biosynthetic process
GO:0009156
IEA
Genome Projectribonucleoside monophosphate biosynthetic process
GO:0009168
TAS
Genome Projectpurine ribonucleoside monophosphate biosynthetic process
GO:0010033
IEA
Genome Projectresponse to organic substance
GO:0010035
IEA
Genome Projectresponse to inorganic substance
GO:0021549
IEA
Genome Projectcerebellum development
GO:0021987
IEA
Genome Projectcerebral cortex development
GO:0032259
IEA
Genome Projectmethylation
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0046654
IEA
Genome Projecttetrahydrofolate biosynthetic process
GO:0055086
TAS
Genome Projectnucleobase-containing small molecule metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0003824
IEA
Genome Projectcatalytic activity
GO:0004637
IEA
Genome Projectphosphoribosylamine-glycine ligase activity
GO:0004641
IEA
Genome Projectphosphoribosylformylglycinamidine cyclo-ligase activity
GO:0004644
TAS, IEA
Genome Projectphosphoribosylglycinamide formyltransferase activity
GO:0005524
IEA
Genome ProjectATP binding
GO:0008168
IEA
Genome Projectmethyltransferase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0016742
IEA
Genome Projecthydroxymethyl-, formyl- and related transferase activity
GO:0016874
IEA
Genome Projectligase activity
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000115Phosphoribosylglycinamide synthetase
IPR001555Phosphoribosylglycinamide formyltransferase, active site
IPR002376Formyl transferase, N-terminal
IPR004607Phosphoribosylglycinamide formyltransferase
IPR004733Phosphoribosylformylglycinamidine cyclo-ligase
IPR010918AIR synthase-related protein, C-terminal domain
IPR011054Rudiment single hybrid motif
IPR011761ATP-grasp fold
IPR013815ATP-grasp fold, subdomain 1
IPR013816ATP-grasp fold, subdomain 2
IPR016185Pre-ATP-grasp domain
IPR016188PurM-like, N-terminal domain
IPR020559Phosphoribosylglycinamide synthetase, conserved site
IPR020560Phosphoribosylglycinamide synthetase, C-domain
IPR020561Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
IPR020562Phosphoribosylglycinamide synthetase, N-terminal

No MapMan annotations defined for this gene.