Gene: ENSG00000158941 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000158941
Transcript Identifier
ENST00000389279
Gene Type
Coding gene
Location
8 : 22605774-22619682 : positive

Family Information

Homologous gene family
HOM03P020515
(4 genes in 2 species)
specific family
Orthologous gene family
ORTHO03P063855
(2 genes in 2 species)
specific family

Descriptions

gene_descr
cell cycle and apoptosis regulator 2

Identifiers

Type Value
pidENSP00000373930
HGNC23360
UniprotQ8N163

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006397
IEA
Genome ProjectmRNA processing
GO:0006915
IEA
Genome Projectapoptotic process
GO:0006974
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0007049
IEA
Genome Projectcell cycle
GO:0008380
IMP
IEA
Genome ProjectRNA splicing
GO:0009411
IMP
Genome Projectresponse to UV
GO:0016055
IEA
Genome ProjectWnt signaling pathway
GO:0030308
IMP
Genome Projectnegative regulation of cell growth
GO:0031647
IDA
Genome Projectregulation of protein stability
GO:0032435
IDA
Genome Projectnegative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032784
IMP
Genome Projectregulation of DNA-templated transcription, elongation
GO:0034605
TAS
Genome Projectcellular response to heat
GO:0042752
ISS
IEA
Genome Projectregulation of circadian rhythm
GO:0043065
IMP
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043086
IMP
Genome Projectnegative regulation of catalytic activity
GO:0043653
IDA
Genome Projectmitochondrial fragmentation involved in apoptotic process
GO:0045892
IDA, IMP
Genome Projectnegative regulation of transcription, DNA-templated
GO:0048511
IEA
Genome Projectrhythmic process
GO:0090263
IMP
Genome Projectpositive regulation of canonical Wnt signaling pathway
GO:0090311
IDA
Genome Projectregulation of protein deacetylation
GO:1900034
TAS
Genome Projectregulation of cellular response to heat
GO:1902230
IMP
Genome Projectnegative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:2000003
IMP
Genome Projectpositive regulation of DNA damage checkpoint

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000993
IDA
Genome ProjectRNA polymerase II core binding
GO:0004857
IDA, IMP
IEA
Genome Projectenzyme inhibitor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0019899
IPI
Genome Projectenzyme binding
GO:0044822
IDA
Genome Projectpoly(A) RNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000790
IDA
Genome Projectnuclear chromatin
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005759
IDA
Genome Projectmitochondrial matrix
GO:0044609
IDA
IEA
Genome ProjectDBIRD complex
GO:0005681
IDA
Genome Projectspliceosomal complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR025223S1-like RNA binding domain
IPR025224Cell cycle and apoptosis regulator protein
IPR025954DBC1/CARP1 catalytically inactive NUDIX hydrolase domain
IPR028811Cell cycle and apoptosis regulator protein 2

No MapMan annotations defined for this gene.