Gene: ENSG00000158856 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000158856
Transcript Identifier
ENST00000358242
Gene Type
Coding gene
Location
8 : 22066876-22081463 : positive

Family Information

Homologous gene family
HOM03P006648
(13 genes in 6 species)
specific family
Orthologous gene family
ORTHO03P074422
(2 genes in 2 species)
specific family

Descriptions

gene_descr
dematin actin binding protein

Identifiers

Type Value
pidENSP00000350977
HGNC3382
UniprotQ08495

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006461
IDA
ISS
Genome Projectprotein complex assembly
GO:0007010
TAS, IEA
Genome Projectcytoskeleton organization
GO:0008360
IMP
Genome Projectregulation of cell shape
GO:0010591
IMP
Genome Projectregulation of lamellipodium assembly
GO:0010763
ISS
IEA
Genome Projectpositive regulation of fibroblast migration
GO:0010801
ISS
IEA
Genome Projectnegative regulation of peptidyl-threonine phosphorylation
GO:0010812
ISS
IEA
Genome Projectnegative regulation of cell-substrate adhesion
GO:0030036
ISS
IEA
Genome Projectactin cytoskeleton organization
GO:0030194
ISS
IEA
Genome Projectpositive regulation of blood coagulation
GO:0032956
IDA
Genome Projectregulation of actin cytoskeleton organization
GO:0033137
ISS
IEA
Genome Projectnegative regulation of peptidyl-serine phosphorylation
GO:0035584
ISS
IEA
Genome Projectcalcium-mediated signaling using intracellular calcium source
GO:0035585
ISS
Genome Projectcalcium-mediated signaling using extracellular calcium source
GO:0048821
ISS
IEA
Genome Projecterythrocyte development
GO:0050732
ISS
IEA
Genome Projectnegative regulation of peptidyl-tyrosine phosphorylation
GO:0051017
IDA
TAS
Genome Projectactin filament bundle assembly
GO:0051489
IMP
Genome Projectregulation of filopodium assembly
GO:0051693
IEA
Genome Projectactin filament capping
GO:0051895
ISS
IEA
Genome Projectnegative regulation of focal adhesion assembly
GO:0055085
TAS
Genome Projecttransmembrane transport
GO:0070560
ISS
IEA
Genome Projectprotein secretion by platelet
GO:0071277
ISS
IEA
Genome Projectcellular response to calcium ion
GO:0071320
IDA
Genome Projectcellular response to cAMP
GO:0090303
ISS
IEA
Genome Projectpositive regulation of wound healing
GO:0090315
ISS
IEA
Genome Projectnegative regulation of protein targeting to membrane
GO:0090527
ISS
IEA
Genome Projectactin filament reorganization
GO:1900025
ISS
IEA
Genome Projectnegative regulation of substrate adhesion-dependent cell spreading
GO:1900026
ISS
IEA
Genome Projectpositive regulation of substrate adhesion-dependent cell spreading
GO:1901731
ISS
IEA
Genome Projectpositive regulation of platelet aggregation
GO:2001046
ISS
IEA
Genome Projectpositive regulation of integrin-mediated signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003779
IDA
IEA
Genome Projectactin binding
GO:0005102
IDA
Genome Projectreceptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0030507
IDA
Genome Projectspectrin binding
GO:0043621
IDA
Genome Projectprotein self-association

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005829
IDA
TAS, IEA
Genome Projectcytosol
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005884
IDA
Genome Projectactin filament
GO:0005886
IDA
IEA
Genome Projectplasma membrane
GO:0012505
IEA
Genome Projectendomembrane system
GO:0014731
IDA
Genome Projectspectrin-associated cytoskeleton
GO:0015629
TAS
Genome Projectactin cytoskeleton
GO:0016020
IEA
Genome Projectmembrane
GO:0016023
IDA
Genome Projectcytoplasmic membrane-bounded vesicle
GO:0030863
IEA
Genome Projectcortical cytoskeleton
GO:0031095
IDA
Genome Projectplatelet dense tubular network membrane
GO:0031253
ISS
IEA
Genome Projectcell projection membrane
GO:0042995
IEA
Genome Projectcell projection
GO:0048471
ISS
IEA
Genome Projectperinuclear region of cytoplasm
GO:0097481
IEA
Genome Projectneuronal postsynaptic density

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003128Villin headpiece
IPR032402Putative adherens-junction anchoring domain

No MapMan annotations defined for this gene.