Gene: ENSG00000158578 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000158578
Transcript Identifier
ENST00000330807
Gene Type
Coding gene
Location
X : 55009180-55026000 : negative

Family Information

Homologous gene family
HOM03P000258
(144 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P007688
(11 genes in 8 species)
specific family

Descriptions

gene_descr
5'-aminolevulinate synthase 2

Identifiers

Type Value
pidENSP00000332369
HGNC397
UniprotP22557

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001666
IDA
Genome Projectresponse to hypoxia
GO:0006778
TAS, IEA
Genome Projectporphyrin-containing compound metabolic process
GO:0006782
IEA
Genome Projectprotoporphyrinogen IX biosynthetic process
GO:0006783
ISS
TAS, NAS, IEA
Genome Projectheme biosynthetic process
GO:0006879
ISS
IEA
Genome Projectcellular iron ion homeostasis
GO:0008152
IEA
Genome Projectmetabolic process
GO:0009058
IEA
Genome Projectbiosynthetic process
GO:0030218
ISS
NAS, IEA
Genome Projecterythrocyte differentiation
GO:0032364
NAS
Genome Projectoxygen homeostasis
GO:0033014
IEA
Genome Projecttetrapyrrole biosynthetic process
GO:0042541
ISS
IEA
Genome Projecthemoglobin biosynthetic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003824
IEA
Genome Projectcatalytic activity
GO:0003870
IDA
IEA
Genome Project5-aminolevulinate synthase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0016594
ISS
Genome Projectglycine binding
GO:0016740
IEA
Genome Projecttransferase activity
GO:0016746
IEA
Genome Projecttransferase activity, transferring acyl groups
GO:0030170
IEA
Genome Projectpyridoxal phosphate binding
GO:0050662
ISS
Genome Projectcoenzyme binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005739
IDA
IEA
Genome Projectmitochondrion
GO:0005743
IDA
Genome Projectmitochondrial inner membrane
GO:0005759
TAS, IEA
Genome Projectmitochondrial matrix

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001917Aminotransferase, class-II, pyridoxal-phosphate binding site
IPR004839Aminotransferase, class I/classII
IPR010961Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase
IPR0151185-aminolevulinate synthase presequence
IPR015421Pyridoxal phosphate-dependent transferase, major region, subdomain 1
IPR015422Pyridoxal phosphate-dependent transferase, major region, subdomain 2
IPR015424Pyridoxal phosphate-dependent transferase

No MapMan annotations defined for this gene.