Gene: ENSG00000157557 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000157557
Transcript Identifier
ENST00000360938
Gene Type
Coding gene
Location
21 : 38810035-38822889 : positive

Family Information

Homologous gene family
HOM03P001388
(52 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P076571
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
v-ets avian erythroblastosis virus E26 oncogene homolog 2

Identifiers

Type Value
pidENSP00000354194
HGNC3489
UniprotP15036

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001501
TAS
Genome Projectskeletal system development
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0007498
IEA
Genome Projectmesoderm development
GO:0030154
IBA
Genome Projectcell differentiation
GO:0045893
IDA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0090009
IEA
Genome Projectprimitive streak formation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000977
IEA
Genome ProjectRNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978
IDA
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078
IDA
Genome Projecttranscriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003677
TAS, IEA
Genome ProjectDNA binding
GO:0003700
IDA
NAS, IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0035259
IEA
Genome Projectglucocorticoid receptor binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000418Ets domain
IPR003118Pointed domain
IPR011991Winged helix-turn-helix DNA-binding domain
IPR013761Sterile alpha motif/pointed domain
IPR016311Transforming protein C-ets
IPR027276Transforming protein C-ets-2

No MapMan annotations defined for this gene.