Gene: ENSG00000157240 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000157240
Transcript Identifier
ENST00000287934
Gene Type
Coding gene
Location
7 : 91264881-91266824 : positive

Family Information

Homologous gene family
HOM03P002165
(40 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P011847
(7 genes in 3 species)
specific family

Descriptions

gene_descr
frizzled class receptor 1

Identifiers

Type Value
pidENSP00000287934
HGNC4038
UniprotQ9UP38

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001934
IEA
Genome Projectpositive regulation of protein phosphorylation
GO:0003149
IEA
Genome Projectmembranous septum morphogenesis
GO:0003150
IEA
Genome Projectmuscular septum morphogenesis
GO:0003151
IEA
Genome Projectoutflow tract morphogenesis
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007166
IEA
Genome Projectcell surface receptor signaling pathway
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007267
IDA
Genome Projectcell-cell signaling
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0016055
IEA
Genome ProjectWnt signaling pathway
GO:0030182
ISS
Genome Projectneuron differentiation
GO:0030514
IEA
Genome Projectnegative regulation of BMP signaling pathway
GO:0030855
IEA
Genome Projectepithelial cell differentiation
GO:0035414
IEA
Genome Projectnegative regulation of catenin import into nucleus
GO:0035425
IDA
Genome Projectautocrine signaling
GO:0035567
IBA
Genome Projectnon-canonical Wnt signaling pathway
GO:0042493
IMP
Genome Projectresponse to drug
GO:0044338
IMP
Genome Projectcanonical Wnt signaling pathway involved in mesenchymal stem cell differentiation
GO:0044339
IMP
Genome Projectcanonical Wnt signaling pathway involved in osteoblast differentiation
GO:0045667
IEA
Genome Projectregulation of osteoblast differentiation
GO:0045892
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
IDA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0048286
IEA
Genome Projectlung alveolus development
GO:0051091
IDA
Genome Projectpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0060022
IEA
Genome Projecthard palate development
GO:0060070
IDA
Genome Projectcanonical Wnt signaling pathway
GO:0060412
IEA
Genome Projectventricular septum morphogenesis
GO:0071305
IEA
Genome Projectcellular response to vitamin D
GO:0071363
IEA
Genome Projectcellular response to growth factor stimulus
GO:0071375
IEA
Genome Projectcellular response to peptide hormone stimulus
GO:0090090
IEA
Genome Projectnegative regulation of canonical Wnt signaling pathway
GO:0090179
IEA
Genome Projectplanar cell polarity pathway involved in neural tube closure
GO:0090263
TAS
Genome Projectpositive regulation of canonical Wnt signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004888
IEA
Genome Projecttransmembrane signaling receptor activity
GO:0004930
IBA
IEA
Genome ProjectG-protein coupled receptor activity
GO:0005102
IPI
Genome Projectreceptor binding
GO:0005109
IPI
Genome Projectfrizzled binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0017147
IPI
Genome ProjectWnt-protein binding
GO:0030165
IPI
Genome ProjectPDZ domain binding
GO:0042813
IDA
IEA
Genome ProjectWnt-activated receptor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005925
IDA
Genome Projectfocal adhesion
GO:0009986
IDA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IBA
IEA
Genome Projectintegral component of membrane
GO:0043005
IEA
Genome Projectneuron projection

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000539Frizzled protein
IPR015526Frizzled/secreted frizzled-related protein
IPR017981GPCR, family 2-like
IPR020067Frizzled domain
IPR026548Frizzled-1

No MapMan annotations defined for this gene.