Gene: ENSG00000156427 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000156427
Transcript Identifier
ENST00000274625
Gene Type
Coding gene
Location
5 : 171420200-171456805 : positive

Family Information

Homologous gene family
HOM03P015492
(5 genes in 3 species)
specific family
Orthologous gene family
ORTHO03P064425
(2 genes in 2 species)
specific family

Descriptions

gene_descr
fibroblast growth factor 18

Identifiers

Type Value
pidENSP00000274625
HGNC3674
UniprotO76093

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001503
IEA
Genome Projectossification
GO:0001525
IEA
Genome Projectangiogenesis
GO:0001957
IEA
Genome Projectintramembranous ossification
GO:0001958
IEA
Genome Projectendochondral ossification
GO:0002063
IEA
Genome Projectchondrocyte development
GO:0007165
TAS
Genome Projectsignal transduction
GO:0007173
TAS
Genome Projectepidermal growth factor receptor signaling pathway
GO:0007267
TAS
Genome Projectcell-cell signaling
GO:0008284
TAS, IEA
Genome Projectpositive regulation of cell proliferation
GO:0008286
TAS
Genome Projectinsulin receptor signaling pathway
GO:0008543
TAS, IEA
Genome Projectfibroblast growth factor receptor signaling pathway
GO:0009653
TAS
Genome Projectanatomical structure morphogenesis
GO:0030324
IEA
Genome Projectlung development
GO:0030949
IEA
Genome Projectpositive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0032332
IEA
Genome Projectpositive regulation of chondrocyte differentiation
GO:0038095
TAS
Genome ProjectFc-epsilon receptor signaling pathway
GO:0043406
IDA
Genome Projectpositive regulation of MAP kinase activity
GO:0045087
TAS
Genome Projectinnate immune response
GO:0048011
TAS
Genome Projectneurotrophin TRK receptor signaling pathway
GO:0048015
TAS
Genome Projectphosphatidylinositol-mediated signaling
GO:0070374
IC, IEA
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:2000546
IDA
Genome Projectpositive regulation of endothelial cell chemotaxis to fibroblast growth factor
GO:0001936
IDA
Genome Projectregulation of endothelial cell proliferation
GO:1903670
IDA
Genome Projectregulation of sprouting angiogenesis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005102
IEA
Genome Projectreceptor binding
GO:0005104
IEA
Genome Projectfibroblast growth factor receptor binding
GO:0005105
IDA
Genome Projecttype 1 fibroblast growth factor receptor binding
GO:0005111
IDA
Genome Projecttype 2 fibroblast growth factor receptor binding
GO:0008083
TAS, IEA
Genome Projectgrowth factor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS, IEA
Genome Projectextracellular region
GO:0005615
TAS
Genome Projectextracellular space
GO:0005730
IDA
Genome Projectnucleolus

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR002209Fibroblast growth factor family
IPR008996Cytokine, IL-1-like
IPR028142IL-1 family/FGF family
IPR028289Fibroblast growth factor 18

No MapMan annotations defined for this gene.