Gene: ENSG00000156234 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000156234
Transcript Identifier
ENST00000286758
Gene Type
Coding gene
Location
4 : 77605866-77611039 : positive

Family Information

Homologous gene family
HOM03P039748
(2 genes in 2 species)
specific family

Descriptions

gene_descr
chemokine (C-X-C motif) ligand 13

Identifiers

Type Value
pidENSP00000286758
HGNC10639
UniprotO43927
UniprotQ53X90

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002467
NAS
Genome Projectgerminal center formation
GO:0002518
ISS
IEA
Genome Projectlymphocyte chemotaxis across high endothelial venule
GO:0002544
NAS
Genome Projectchronic inflammatory response
GO:0002920
NAS
Genome Projectregulation of humoral immune response
GO:0006935
IEA
Genome Projectchemotaxis
GO:0006954
IBA
IEA
Genome Projectinflammatory response
GO:0006955
IBA
IC, IEA
Genome Projectimmune response
GO:0007166
IDA
Genome Projectcell surface receptor signaling pathway
GO:0007186
IBA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007204
IDA
Genome Projectpositive regulation of cytosolic calcium ion concentration
GO:0007267
IDA
Genome Projectcell-cell signaling
GO:0010820
IDA
Genome Projectpositive regulation of T cell chemotaxis
GO:0032496
IBA
Genome Projectresponse to lipopolysaccharide
GO:0033625
ISS
IEA
Genome Projectpositive regulation of integrin activation
GO:0033634
ISS
IEA
Genome Projectpositive regulation of cell-cell adhesion mediated by integrin
GO:0035754
IDA
Genome ProjectB cell chemotaxis
GO:0035768
IDA
Genome Projectendothelial cell chemotaxis to fibroblast growth factor
GO:0035769
IEA
Genome ProjectB cell chemotaxis across high endothelial venule
GO:0042127
IBA
Genome Projectregulation of cell proliferation
GO:0042742
IDA
Genome Projectdefense response to bacterium
GO:0045765
NAS
Genome Projectregulation of angiogenesis
GO:0048535
IEA
Genome Projectlymph node development
GO:0070098
IBA
Genome Projectchemokine-mediated signaling pathway
GO:0090630
ISS
IEA
Genome Projectactivation of GTPase activity
GO:2000545
IDA
Genome Projectnegative regulation of endothelial cell chemotaxis to fibroblast growth factor

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005125
IEA
Genome Projectcytokine activity
GO:0008009
IDA
IEA
Genome Projectchemokine activity
GO:0008201
IDA
Genome Projectheparin binding
GO:0017134
IDA
Genome Projectfibroblast growth factor binding
GO:0031724
IDA
Genome ProjectCXCR5 chemokine receptor binding
GO:0031735
IDA
Genome ProjectCCR10 chemokine receptor binding
GO:0046982
IDA
Genome Projectprotein heterodimerization activity
GO:0048018
IDA
Genome Projectreceptor agonist activity
GO:0048248
IPI
Genome ProjectCXCR3 chemokine receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IDA
TAS, IEA
Genome Projectextracellular region
GO:0005615
IBA
IEA
Genome Projectextracellular space
GO:0005829
IDA
Genome Projectcytosol

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001089CXC chemokine
IPR001811Chemokine interleukin-8-like domain
IPR018048CXC chemokine, conserved site

No MapMan annotations defined for this gene.