Gene: ENSG00000154743 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000154743
Transcript Identifier
ENST00000284995
Gene Type
Coding gene
Location
3 : 12489801-12532721 : positive

Family Information

Homologous gene family
HOM03P004634
(20 genes in 17 species)
specific family

Descriptions

gene_descr
TSEN2 tRNA splicing endonuclease subunit

Identifiers

Type Value
pidENSP00000284995
HGNC28422
UniprotQ8NCE0
UniprotA0A024R2H2

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006388
IDA
IEA
Genome ProjecttRNA splicing, via endonucleolytic cleavage and ligation
GO:0008033
IEA
Genome ProjecttRNA processing
GO:0090305
IEA
Genome Projectnucleic acid phosphodiester bond hydrolysis
GO:0090501
IBA
IEA
Genome ProjectRNA phosphodiester bond hydrolysis
GO:0090502
IBA
IEA
Genome ProjectRNA phosphodiester bond hydrolysis, endonucleolytic
GO:0000379
IBA
Genome ProjecttRNA-type intron splice site recognition and cleavage
GO:0006397
IEA
Genome ProjectmRNA processing

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000213
IBA
IEA
Genome ProjecttRNA-intron endonuclease activity
GO:0003676
IEA
Genome Projectnucleic acid binding
GO:0004518
IEA
Genome Projectnuclease activity
GO:0004519
IEA
Genome Projectendonuclease activity
GO:0016829
IEA
Genome Projectlyase activity
GO:0005515
IPI
Genome Projectprotein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000214
IBA
IEA
Genome ProjecttRNA-intron endonuclease complex
GO:0005634
IEA
Genome Projectnucleus
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005730
IEA
Genome Projectnucleolus
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005813
IDA
Genome Projectcentrosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR006676tRNA-splicing endonuclease
IPR006677tRNA intron endonuclease, catalytic domain-like
IPR006678tRNA intron endonuclease, N-terminal
IPR011856tRNA endonuclease-like domain
IPR016589tRNA-splicing endonuclease, SEN2 subunit

No MapMan annotations defined for this gene.