Gene: ENSG00000154727 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000154727
Transcript Identifier
ENST00000400075
Gene Type
Coding gene
Location
21 : 25741599-25769232 : positive

Family Information

Homologous gene family
HOM03P001388
(52 genes in 4 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
GA binding protein transcription factor, alpha subunit 60kDa

Identifiers

Type Value
pidENSP00000382948
HGNC4071
UniprotQ06546
UniprotA8IE48

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001701
IEA
Genome Projectin utero embryonic development
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IEA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0045653
IEA
Genome Projectnegative regulation of megakaryocyte differentiation
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006366
TAS
Genome Projecttranscription from RNA polymerase II promoter
GO:0006996
TAS
Genome Projectorganelle organization
GO:0007005
TAS
Genome Projectmitochondrion organization
GO:0030154
IBA
Genome Projectcell differentiation
GO:0045944
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003677
TAS, IEA
Genome ProjectDNA binding
GO:0003682
IEA
Genome Projectchromatin binding
GO:0003700
TAS, IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding
GO:0000978
IDA
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077
IDA
Genome Projecttranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001228
IDA
Genome Projecttranscriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0003713
TAS
Genome Projecttranscription coactivator activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0044212
IDA
Genome Projecttranscription regulatory region DNA binding
GO:0046982
IDA
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
TAS, IEA
Genome Projectnucleus
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0000790
IDA
Genome Projectnuclear chromatin

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000418Ets domain
IPR003118Pointed domain
IPR011991Winged helix-turn-helix DNA-binding domain
IPR013761Sterile alpha motif/pointed domain
IPR016312Transcription factor, GA-binding, alpha subunit
IPR024668GA-binding protein alpha subunit, N-terminal
IPR029071Ubiquitin-related domain

No MapMan annotations defined for this gene.