Gene: ENSG00000154358 (Homo sapiens)

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Gene Identifier
ENSG00000154358
Transcript Identifier
ENST00000366707
Gene Type
Coding gene
Location
1 : 228211784-228378795 : positive

Family Information

Homologous gene family
HOM03P000274
(139 genes in 9 species)
specific family
Orthologous gene family
ORTHO03P066261
(2 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
obscurin, cytoskeletal calmodulin and titin- interacting RhoGEF

Identifiers

Type Value
pidENSP00000355668
HGNC15719
UniprotA6NGQ3

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006468
IEA
Genome Projectprotein phosphorylation
GO:0016310
IEA
Genome Projectphosphorylation
GO:0035023
IEA
Genome Projectregulation of Rho protein signal transduction
GO:0043547
IEA
Genome Projectpositive regulation of GTPase activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0005089
IEA
Genome ProjectRho guanyl-nucleotide exchange factor activity
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000048IQ motif, EF-hand binding site
IPR000219Dbl homology (DH) domain
IPR000719Protein kinase domain
IPR001452SH3 domain
IPR001849Pleckstrin homology domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR003006Immunoglobulin/major histocompatibility complex, conserved site
IPR003598Immunoglobulin subtype 2
IPR003599Immunoglobulin subtype
IPR003961Fibronectin type III
IPR007110Immunoglobulin-like domain
IPR008266Tyrosine-protein kinase, active site
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR011993PH domain-like
IPR013098Immunoglobulin I-set
IPR013106Immunoglobulin V-set domain
IPR013783Immunoglobulin-like fold
IPR017441Protein kinase, ATP binding site

No MapMan annotations defined for this gene.