Gene: ENSG00000153094 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000153094
Transcript Identifier
ENST00000393256
Gene Type
Coding gene
Location
2 : 111123746-111164231 : positive

Family Information

Homologous gene family
HOM03P048889
(2 genes in 2 species)
specific family

Descriptions

gene_descr
BCL2-like 11 (apoptosis facilitator)

Identifiers

Type Value
pidENSP00000376943
HGNC994
UniprotO43521

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001701
IEA
Genome Projectin utero embryonic development
GO:0001776
IEA
Genome Projectleukocyte homeostasis
GO:0001782
IEA
Genome ProjectB cell homeostasis
GO:0001783
IEA
Genome ProjectB cell apoptotic process
GO:0001822
IEA
Genome Projectkidney development
GO:0002260
IEA
Genome Projectlymphocyte homeostasis
GO:0002262
IEA
Genome Projectmyeloid cell homeostasis
GO:0006915
TAS, IEA
Genome Projectapoptotic process
GO:0006919
IDA
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007160
IEA
Genome Projectcell-matrix adhesion
GO:0007283
IEA
Genome Projectspermatogenesis
GO:0007420
IEA
Genome Projectbrain development
GO:0008584
IEA
Genome Projectmale gonad development
GO:0008630
IDA
Genome Projectintrinsic apoptotic signaling pathway in response to DNA damage
GO:0009791
IEA
Genome Projectpost-embryonic development
GO:0010942
IEA
Genome Projectpositive regulation of cell death
GO:0012501
TAS
Genome Projectprogrammed cell death
GO:0030879
IEA
Genome Projectmammary gland development
GO:0032464
IDA
Genome Projectpositive regulation of protein homooligomerization
GO:0034976
IDA
Genome Projectresponse to endoplasmic reticulum stress
GO:0035148
IEA
Genome Projecttube formation
GO:0042475
IEA
Genome Projectodontogenesis of dentin-containing tooth
GO:0042981
IEA
Genome Projectregulation of apoptotic process
GO:0043029
IEA
Genome ProjectT cell homeostasis
GO:0043065
IMP
TAS
Genome Projectpositive regulation of apoptotic process
GO:0043280
IEA
Genome Projectpositive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043525
IEA
Genome Projectpositive regulation of neuron apoptotic process
GO:0043583
IEA
Genome Projectear development
GO:0045787
IEA
Genome Projectpositive regulation of cell cycle
GO:0046620
IEA
Genome Projectregulation of organ growth
GO:0048011
TAS
Genome Projectneurotrophin TRK receptor signaling pathway
GO:0048066
IEA
Genome Projectdevelopmental pigmentation
GO:0048070
IEA
Genome Projectregulation of developmental pigmentation
GO:0048536
IEA
Genome Projectspleen development
GO:0048538
IEA
Genome Projectthymus development
GO:0048563
IEA
Genome Projectpost-embryonic organ morphogenesis
GO:0060139
IEA
Genome Projectpositive regulation of apoptotic process by virus
GO:0060154
IEA
Genome Projectcellular process regulating host cell cycle in response to virus
GO:0070242
IEA
Genome Projectthymocyte apoptotic process
GO:0090200
IMP, IGI
Genome Projectpositive regulation of release of cytochrome c from mitochondria
GO:0097190
TAS
Genome Projectapoptotic signaling pathway
GO:0097192
IEA
Genome Projectextrinsic apoptotic signaling pathway in absence of ligand
GO:0097193
TAS
Genome Projectintrinsic apoptotic signaling pathway
GO:1900740
TAS
Genome Projectpositive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:1902110
IEA
Genome Projectpositive regulation of mitochondrial membrane permeability involved in apoptotic process
GO:1902237
TAS
Genome Projectpositive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:1902263
IEA
Genome Projectapoptotic process involved in embryonic digit morphogenesis
GO:1903896
TAS
Genome Projectpositive regulation of IRE1-mediated unfolded protein response
GO:2000271
IDA
Genome Projectpositive regulation of fibroblast apoptotic process
GO:2001244
IMP
TAS
Genome Projectpositive regulation of intrinsic apoptotic signaling pathway
GO:0007127
IBA
Genome Projectmeiosis I

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0008017
IDA
IEA
Genome Projectmicrotubule binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005739
IBA
IEA
Genome Projectmitochondrion
GO:0005741
TAS
Genome Projectmitochondrial outer membrane
GO:0005829
IDA
TAS
Genome Projectcytosol
GO:0012505
IEA
Genome Projectendomembrane system
GO:0016020
IEA
Genome Projectmembrane
GO:0019898
IEA
Genome Projectextrinsic component of membrane
GO:0043231
IEA
Genome Projectintracellular membrane-bounded organelle
GO:0097140
IDA
Genome ProjectBIM-BCL-xl complex
GO:0097141
IDA
Genome ProjectBIM-BCL-2 complex
GO:0005874
IDA
Genome Projectmicrotubule

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR014771Apoptosis, Bim N-terminal
IPR015040Bcl-x interacting, BH3 domain
IPR017288Bcl-2-like protein 11

No MapMan annotations defined for this gene.