Gene: ENSG00000151491 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000151491
Transcript Identifier
ENST00000543612
Gene Type
Coding gene
Location
12 : 15621317-15682951 : negative

Family Information

Homologous gene family
HOM03P012143
(7 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P029382
(4 genes in 4 species)
specific family

Descriptions

gene_descr
epidermal growth factor receptor pathway substrate 8

Identifiers

Type Value
pidENSP00000442388
HGNC3420
UniprotQ12929

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007165
TAS
Genome Projectsignal transduction
GO:0007173
TAS
Genome Projectepidermal growth factor receptor signaling pathway
GO:0008283
TAS
Genome Projectcell proliferation
GO:0008344
IEA
Genome Projectadult locomotory behavior
GO:0008360
ISS
IEA
Genome Projectregulation of cell shape
GO:0009967
TAS, IEA
Genome Projectpositive regulation of signal transduction
GO:0010458
ISS
IEA
Genome Projectexit from mitosis
GO:0016601
ISS
IEA
Genome ProjectRac protein signal transduction
GO:0030832
ISS
IEA
Genome Projectregulation of actin filament length
GO:0031532
IEA
Genome Projectactin cytoskeleton reorganization
GO:0036336
ISS
IEA
Genome Projectdendritic cell migration
GO:0048149
IEA
Genome Projectbehavioral response to ethanol
GO:0051016
ISS
IEA
Genome Projectbarbed-end actin filament capping
GO:0051017
ISS
IEA
Genome Projectactin filament bundle assembly
GO:0051764
ISS
IEA
Genome Projectactin crosslink formation
GO:0070358
ISS
IEA
Genome Projectactin polymerization-dependent cell motility

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003779
ISS
IEA
Genome Projectactin binding
GO:0005070
TAS
Genome ProjectSH3/SH2 adaptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0035591
IEA
Genome Projectsignaling adaptor activity
GO:0048365
ISS
IEA
Genome ProjectRac GTPase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005886
IEA
Genome Projectplasma membrane
GO:0005903
IEA
Genome Projectbrush border
GO:0005938
ISS
IEA
Genome Projectcell cortex
GO:0014069
IEA
Genome Projectpostsynaptic density
GO:0016020
IEA
Genome Projectmembrane
GO:0017146
IEA
Genome ProjectNMDA selective glutamate receptor complex
GO:0030054
IEA
Genome Projectcell junction
GO:0030426
IEA
Genome Projectgrowth cone
GO:0031982
IDA
Genome Projectvesicle
GO:0032420
ISS
IEA
Genome Projectstereocilium
GO:0032587
ISS
IEA
Genome Projectruffle membrane
GO:0042995
IEA
Genome Projectcell projection
GO:0043005
IEA
Genome Projectneuron projection
GO:0045202
IEA
Genome Projectsynapse
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001452SH3 domain
IPR006020PTB/PI domain
IPR011993PH domain-like
IPR013625Tensin phosphotyrosine-binding domain
IPR030222Epidermal growth factor receptor kinase substrate 8

No MapMan annotations defined for this gene.