Gene: ENSG00000150768 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000150768
Transcript Identifier
ENST00000280346
Gene Type
Coding gene
Location
11 : 112025473-112062535 : positive

Family Information

Homologous gene family
HOM03P000118
(242 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000891
(42 genes in 37 species)
specific family

Descriptions

gene_descr
dihydrolipoamide S-acetyltransferase

Identifiers

Type Value
pidENSP00000280346
HGNC2896
UniprotP10515
UniprotQ86YI5

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005975
IEA
Genome Projectcarbohydrate metabolic process
GO:0006006
IEA
Genome Projectglucose metabolic process
GO:0006086
IEA
Genome Projectacetyl-CoA biosynthetic process from pyruvate
GO:0006090
TAS, IEA
Genome Projectpyruvate metabolic process
GO:0006099
IEA
Genome Projecttricarboxylic acid cycle
GO:0008152
IEA
Genome Projectmetabolic process
GO:0010510
TAS
Genome Projectregulation of acetyl-CoA biosynthetic process from pyruvate
GO:0030431
IEA
Genome Projectsleep
GO:0044237
TAS
Genome Projectcellular metabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004742
NAS, IEA
Genome Projectdihydrolipoyllysine-residue acetyltransferase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0016740
IEA
Genome Projecttransferase activity
GO:0016746
IEA
Genome Projecttransferase activity, transferring acyl groups

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005739
IDA
IEA
Genome Projectmitochondrion
GO:0005759
TAS, IEA
Genome Projectmitochondrial matrix
GO:0005967
NAS
Genome Projectmitochondrial pyruvate dehydrogenase complex
GO:0043209
IEA
Genome Projectmyelin sheath
GO:0045254
IDA
IEA
Genome Projectpyruvate dehydrogenase complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000089Biotin/lipoyl attachment
IPR0010782-oxoacid dehydrogenase acyltransferase, catalytic domain
IPR0030162-oxo acid dehydrogenase, lipoyl-binding site
IPR004167E3-binding domain
IPR006257Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex
IPR011053Single hybrid motif
IPR023213Chloramphenicol acetyltransferase-like domain

No MapMan annotations defined for this gene.